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HAEMATOLOGY > [b12/pernicious] > Flashcards

[b12/pernicious] Flashcards

1
Q
A

meat
fish
dairy

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2
Q
A

4 years

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3
Q
A

intrinsic factor

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4
Q
A

thymidine

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5
Q
A

pernicious anaemia
gastrectomy
low IF

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6
Q
A 
ileal resection
Crohns
coeliacs
bacterial overgrowth
tapeworm
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7
Q
A

angular stomatitis

glossitis (beefy-red sore tongue)

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8
Q
A

peripheral neuropathy

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9
Q
A

B12 deficiency

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10
Q
A

symmetrical dorsal and corticospinal tracts

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11
Q
A

dorsal - joint position/vibration sense (ataxia)

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12
Q
A

weakness

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13
Q
A

extensor plantars
Lost reflexes at :
ankle
knee

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14
Q
A

Spinothalamic (P+T)

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15
Q
A

Atrophic gastritis (autoimmune)
Loss of IF
achlorhydria

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16
Q
A

A

17
Q
A

carcinoma of stomach

18
Q
A

macrocytic

19
Q
A

hypersegmented polymorphs

20
Q
A

NO - production is stopped

it will be reduced or normal

21
Q
A

pareital cell antibodies (found in 90%, also 10% without)

Intrinsic factor antibodies (specific but lower sens)

22
Q
A

<40

23
Q
A

Hydroxycobalamin 1mg IM

(alternate days for 2 weeks)

1mg IM every 3 months for life

24
Q
A

alternate days every 2 week s

25
Q
A

1mg IM hydroxycobalamin every 3 months

26
Q
A

reticulocytosis after 5 days (therefore increased MCV)

27
Q
A

SACDSC

28
Q
A

oral b12

HAEMATOLOGY (25 decks)

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