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HAEMATOLOGY > [CML] > Flashcards

[CML] Flashcards

1
Q
A

myeloproliferative disorder

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2
Q
A

4

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3
Q
A

Philadelphia Ch. +

Philadelphia Ch. -

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4
Q
A

CML

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5
Q
A

Polycythaemia vera
Essential thrombocytosis
Myelofibrosis

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6
Q
A

rarely

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7
Q
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Philadelphia Chr.

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8
Q
A

t(9:22)

t=translocation

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9
Q
A

BCR:Abl

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10
Q
A

worse

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11
Q
A

massive spenomegaly
hepatomegaly
bruising (platelet dysfunction)

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12
Q
A

chronic/insidious

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13
Q
A

weight loss
sweats
fever
tired

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14
Q
A

Raised (>100x10^9/L)

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15
Q
A

hypercellularity

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16
Q
A

yes (all myeloid line)

17
Q
A

chronic
accelerated
blast transformation

18
Q
A

chronic

19
Q
A

blast transformation

20
Q
A

BCR:Abl gene tyrosine receptor

21
Q
A

imatinib

Nilotinib

22
Q
A

allogenic HLA matched stem cell transplant

23
Q
A

young patients (if risk low)

24
Q
A

Older patients

HAEMATOLOGY (25 decks)

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