[bleedingIx] Flashcards

1
Q
A

extrinsic

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2
Q
A

INR

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3
Q
A

0.9-1.2

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4
Q
A
I
II
V
VII
X
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5
Q
A

Warfarin

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6
Q
A

warfarin

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7
Q
A

INR/prothrombin

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8
Q
A

factor VII

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9
Q
A

increased consumption of multiple clotting factors

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10
Q
A

35-45 seconds

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11
Q
A

the intrinsic

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12
Q
A

heparin

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13
Q
A

binds to anti-thrombin III inhibitor
AT3 activates and inhibits thrombin
thrombin is responsible for fibrin deposition

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14
Q
A

warfarin inhibits synthesis of 1972 factors - K dependent.

7 is only in extrinsic pathway

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15
Q
A

converts fibrinogen to fibrin

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16
Q
A

10-15 seconds

17
Q
A

fibrin degradation products

released from the x-linking during fibrinolysis

18
Q
A

DIC
PE
DVT

19
Q
A

two small cuts in forearm

20
Q
A

<10 mins

21
Q
A

PFA-100

22
Q
A

platelet function analyzer 100

23
Q
A

collagen + adrenaline

collagen + ADP

24
Q

collagen + ADP are abnormal what does this indicate

A

platelet dysfunction is likely - further testing

25
Q
A

aspirin ingestion

26
Q
A

APTT

27
Q
A

IM