Mycoplasma pneumoniae Flashcards
what types of antibiotics are ineffective against M. pneumo?
Abx that interfere with cell wall synthesis
what important cell structure does M. pneumo possess?
M. pneumo possesses a cytoskeleton
what highly immunogenic toxin does M. pneumo possess?
ADP-ribosylating and vacuolating cytotoxin (community acquired RDS toxin)
how is M. pneumo transmitted?
direct contact with/inhalation of aerosols from an infected person
what is the case to case interval for M. pneumo?
23 days
is M. pneumo highly infectious?
no, epidemics are rare except in closed populations
what is the reservoir for M. pneumo?
humans
what age group is most commonly infected with M. pneumo?
4-early 20’s
peak incidence in school children
what is the peak seasonality for M. pneumo?
July-January
what is the key risk factor for M. pneumo?
humoral immunodeficies
CMI compromise
what is a key complication of M. pneumo infx?
brain stem and striatal encephalitis
what is the DDx for M. pneumo?
B. pertussis Chalmydia/Chlamydophila pneumoniae parainfluenzavirus RSV influenza virus adenovirus Human metapneumovirus
what is the main test for M. pneumo?
EIA test for M. pneumo specific IgM or cold agglutinins
what is the treatment for M. pneumo?
macrolides (erythromycin, azithromycin)
tetracyclines
quinolones
