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IDEA > Klebsiella pneumoniae > Flashcards

Klebsiella pneumoniae Flashcards

1
Q

what is the classification of K. pneumo?

A

enteric bacteria

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2
Q

what is the gram stain morphology of K. pneumo?

A

GNR

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3
Q

is K. pneumo fastidious?

A

not fastidious

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4
Q

what are the oxygen growth requirements for K. pneumo?

A

facultative anaerobe

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5
Q

is K. pneumo a fermenter?

A

yes, fermenter

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6
Q

what is the oxidase status of K. pneumo?

A

oxidase negative

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7
Q

is K. pneumo extracellular or intracellular?

A

extracellular bacteria

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8
Q

what is the key virulence factor for K. pneumo?

A

polysaccharide capsule

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9
Q

what is the main funx of the polysaccharide capsule of K. pneumo?

A

mucoid colony formation on agar medium

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10
Q

what are the two most virulent serotypes of K. pneumo?

A

K1

K2

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11
Q

what type (CAP,HAP,HCA-P) pneumo is K. pneumo more involved in?

A

HAP

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12
Q

what type of infx is K. pneumo commonly responsible for in diabetics?

A

UTI

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13
Q

what can bacteremia d/t K. pneumo infx cause, especially in neonates?

A

meningitis

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14
Q

If K. pneumo causes a pyogenic liver abscess, what are two dangerous complications that can result from the infx?

A

septic/pyogenic meningitis

endophthalmitis

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15
Q

what is the transmission of K. pneumo?

A

endogenous (NMF)

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16
Q

what is the reservoir of K. pneumo?

A

endogenous (NMF)

17
Q

are there any special risk factors that separate K. pneumo from the other 4 common agents of acute bacterial pneumo?

A

not really, but meningitis has been mentioned several times, so that might be a tip

18
Q

what type (interstitial,consolidation) of pneumo is K. pneumo most commonly the cause of?

A

consolidation pneumo

19
Q

is K. pneumo an opportunistic or frank pathogen?

A

opportunistic

20
Q

can K. pneumo cause abscess formation/necrotic pneumo?

A

yes, d/t K1/K2 serotypes

21
Q

clinical manifestations buzz words

A

currant (berry) jelly sputum

22
Q

what antibiotics are Panresistant/KPC K. pneumo resistant to?

A

all Abx agents

23
Q

what treatment is used on Ceftazidime-resistant K. pneumo (CRKP)?

A

cefepime
imipenem
(3rd and 4th generation cephalosporins)

24
Q

does K. pneumo infx require isolation?

A

yes, respiratory isolation

25
Q

what is the mortality of K. pneumo caused pneumonia?

A

50%

26
Q

what is the mortality of K. pneumo caused meningitis?

A

100%

27
Q

can K. pneumo be prevented?

A

not currently, but a vaccine is currently in clinical trials

28
Q

What are the 4 A’s of K. pneumo infx?

A

4 A’s mnemonic

Aspiration pneumonia
Abscess in lungs and liver
Alcoholics
di-A-betics

IDEA (30 decks)

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