Klebsiella pneumoniae Flashcards
what is the classification of K. pneumo?
enteric bacteria
what is the gram stain morphology of K. pneumo?
GNR
is K. pneumo fastidious?
not fastidious
what are the oxygen growth requirements for K. pneumo?
facultative anaerobe
is K. pneumo a fermenter?
yes, fermenter
what is the oxidase status of K. pneumo?
oxidase negative
is K. pneumo extracellular or intracellular?
extracellular bacteria
what is the key virulence factor for K. pneumo?
polysaccharide capsule
what is the main funx of the polysaccharide capsule of K. pneumo?
mucoid colony formation on agar medium
what are the two most virulent serotypes of K. pneumo?
K1
K2
what type (CAP,HAP,HCA-P) pneumo is K. pneumo more involved in?
HAP
what type of infx is K. pneumo commonly responsible for in diabetics?
UTI
what can bacteremia d/t K. pneumo infx cause, especially in neonates?
meningitis
If K. pneumo causes a pyogenic liver abscess, what are two dangerous complications that can result from the infx?
septic/pyogenic meningitis
endophthalmitis
what is the transmission of K. pneumo?
endogenous (NMF)
what is the reservoir of K. pneumo?
endogenous (NMF)
are there any special risk factors that separate K. pneumo from the other 4 common agents of acute bacterial pneumo?
not really, but meningitis has been mentioned several times, so that might be a tip
what type (interstitial,consolidation) of pneumo is K. pneumo most commonly the cause of?
consolidation pneumo
is K. pneumo an opportunistic or frank pathogen?
opportunistic
can K. pneumo cause abscess formation/necrotic pneumo?
yes, d/t K1/K2 serotypes
clinical manifestations buzz words
currant (berry) jelly sputum
what antibiotics are Panresistant/KPC K. pneumo resistant to?
all Abx agents
what treatment is used on Ceftazidime-resistant K. pneumo (CRKP)?
cefepime
imipenem
(3rd and 4th generation cephalosporins)
does K. pneumo infx require isolation?
yes, respiratory isolation
