Atypical pneumonias Flashcards
what is the hallmark of atypical pneumonia?
milder symptoms
slower onset
are atypical pneumonia agents fastidious?
yes, all are fastidious
do atypical pneumo agents have peptidoglycan cell walls?
no, all lack peptidoglycan
which atypical pneumo agents lack a cell wall?
Mycoplasma pneumoniae
Ureaplasma urealyticum
Ureaplasma parvum
which atypical pneumo agent posseses a gram negative cell wall but lacks peptidoglycan?
Chlamydia spp.
why is the gram stain not useful for atypical pneumo agents?
small size of agents
what is the main pathogenesis of atypical pneumo agents?
ciliostasis
destruction of ciliated epithelial cells
what type of pneumonia is caused by atypical pneumo agents?
interstitial pneumo
what aspect of atypical pneumo agents causes the insidious onset?
slow growth rate of agents
what aspect of atypical pneumo agents causes the slow spread and long incubation period?
slow growth rate of agents
what aspect of atypical pneumo agents causes the long convalescence period?
slow growth rate of agents
which atypical pneumo agents are extracellular pathogens?
Mycoplasma pneumoniae
Ureaplasma urealyticum
Ureaplasma parvum
which atypical pneumo agents are obligate intracellular pathogens?
Chlamydiae pneumoniae
Chlamydiae trachomatis
which atypical pneumo agent possesses a unique growth cycle including elementary bodies and reticulate bodies?
Chlamydiae spp.
which atypical pneumo agent produces an ADP-ribosylating and vacuolating cytotoxin (community-acquired RDS toxin)?
Mycoplasma pneumoniae
which atypical pneumo agents are transmitted person-to-person via an aerosol route (inhalation of respiratory droplets)?
Mycoplasma pneumoniae
Chlamydia pneumoniae
which atypical pneumo agents are closely associated with vertical transmission (partruition, mother to child)
(mother is often asymptomatic)
Ureaplasma urealyticum
U. parvum
Chlamydia trachomatis
can any atypical agents be visible by gram staining?
no, none
can any atypical pneumo agents be cultured on blood agar?
no, none
-all are fastidious
what type of infiltrate predominates on sputum cultured from an atypical pneumo pt?
monocytic cell infiltrate predominates
what is the length of onset for manifestations of M. pneumo and C. pneumo?
days to 1 week
what manifestations are seen with M. pneumo and C. pneumo?
flu like minus coryza
M. pneumo and C. pneumo clinical buzz words
erythematous pharyngitis with no exudate and no cervical lymphadenopathy
what differentiates M. pneumo infx from C. pneumo infx, clinically speaking?
skin rash for M. pneumo only
