Classifications of fungal pneumonia

Question 1

what immune cell type primarily destroys conidia?

Answer 1

macrophages

Question 2

what immune cell type primarily destroys hyphae?

Answer 2

PMNs

Question 3

what are fungi that infect humans with T cell deficiencies?

Answer 3

T cell opportunists

Question 4

what agents are T cell opportunists?

Answer 4

Histoplasma
Blastomyces
Coccidioides
Cryptococcus
C. albicans
Pneumo j.

Question 5

is CMI required to control infection/disease by fungal agents?

Answer 5

yes

Question 6

can non-immune cells (i.e. the situation in an immunocompromised pt) destroy inhaled fungal spores, thus preventing infection/disease?

Answer 6

no

Question 7

what type of T cell dysfunction patients are at a higher risk for fungal infections?

Answer 7

HIV

glucocorticoids/immunosuppressives

Question 8

what are fungi that infect humans with phagocytic cell deficiencies?

Answer 8

phagocytic cell opportunists

Question 9

what fungal agents are phagocytic cell opportunists?

Answer 9

Aspergillus

Zygomycetes (mucormycosis)

Question 10

individuals with normal function and numbers of PMNs are resistant to infection by what type of fungal agents?

Answer 10

phagocytic cell opportunists

Question 11

what patients are at risk of phagocytic cell opportunist infx?

Answer 11

abnormal or low numbers of PMNs

Question 12

prolonged neutropenia and/or depressed PMN funx predisposes patients to infection by what type of fungal agent?

Answer 12

phagocytic cell opportunists

Question 13

how does unregulated diabetes put a patient at risk for mucormycosis?

Answer 13

depresses PMN funx–>phagocytic cell opportunists

Question 14

what type of fungal infx are dialysis patients at risk for?

Answer 14

phagocytic cell opportunists

Question 15

what type of fungal infx are hemochomatosis pts at risk for?

Answer 15

phagocytic cell opportunists

Question 16

what type of fungal infx are HIV/immunosuppressed patients at risk for?

Answer 16

phagocytic cell opportunists

Question 17

if a patient is IVDU or undergoes a procedure that requires breach of the cutaneous barrier, what type of fungal infx are they at risk for?

Answer 17

phagocytic cell opportunists