Fungi intro Flashcards

1
Q

what type of cells are fungi?

A

eukaryotic

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2
Q

how do fungi reproduce?

A

sexually

asexualy via spores

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3
Q

what are heterotrophs?

A

do not ingest food but parasitize off of living matter

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4
Q

what are the oxygen growth requirements for most fungi?

A

obligate aerobes

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5
Q

what are the oxygen growth requirements for yeast?

A

facultative anaerobes

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6
Q

what is the site of action of most anti-fungal agents?

A

sterols of cell membrane

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7
Q

what differentiates molds?

A

hyphae

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8
Q

what differentiates yeast?

A

budding

mucoid colonies

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9
Q

which form of fungi produces pseudohyphae?

A

yeast (esp. Candida)

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10
Q

what does the germ tube test identify?

A

C. albicans

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11
Q

what mycotic agents are thermally dimorphic?

A

Histoplasma
Blastomyces
Coccidioides
Sporothrix

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12
Q

what type of spores are not encapsulated?

A

Conidia

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13
Q

what size of Conidia is infectious in the RT?

A

Microconidia

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14
Q

what type of spores are thick walled, produced by fragmentation of hyphal cells, and can cause RT infx by inhalation?

A

Arthroconidia

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15
Q

what type of spores are contained within sac-like structures?

A

Sporangiospores

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16
Q

what fungi produce microconidia?

A

Histoplasma
Blastomyces
Aspergillus
Mucormycoses

17
Q

what fungi produce sproangiospores?

A

Coccidioides

PCP

18
Q

if a patient presents with systemic mycosis like symptoms, and a biopsy shows the presence of spherules, what agent is responsible?

A

coccidioidomycoses

19
Q

if a patient presents with systemic mycosis like symptoms, and a CXR shows cysts of 4-6 micrometers in diameter containing intracellular comma-shaped bodies, what agent is responsible?

A

Pneumocystis jiroveci (PCP)

20
Q

what are buds that arise from yeast cells?

A

blastopores

21
Q

what are infections that are confined to the outermost layers of the skin (statum corneum)?

A

superficial mycoses

22
Q

what agents cause superficial mycoses?

A

Malassezia furfur
Piedra hortai
Trichosporon beigelii
Exophiala werneckii

23
Q

what are infections that primarily involve the epidermis, hair, and nails (keratin containing tissue)?

A

cutaneous mycoses

24
Q

what agents cause cutatneous mycoses?

A

Epidermophyton
Microsporum
Trichophyton

25
what special type of cutaneous mycoses is caused by C. albicans?
dermatomycosis
26
what are infections that involve skin, subcutaneous tissue, fascia, and bone?
subcutaneous mycoses
27
what clinical manifestations present with subcutaneous mycoses?
chronic ulcerated lesions with regional lymph node involvement
28
what agents cause subcutaneous mycoses?
``` Sporothrix schenckii chromomycosis mycetoma lobomycosis phaeomycotic cysts ```
29
what are the most serious fungal infections that involve internal organs and viscera?
systemic mycoses
30
what type of mycoses is caused by a POE of the RT, or sometimes a break in the skin too?
systemic mycoses
31
what agents cause systemic mycoses?
Blastomyces Coccidioides Histoplasma Cryptococcus
32
what causes opportunistic mycoses?
NMF | environmental agents
33
what type of therapy can result in opportunistic mycoses?
broad spectrum Abx
34
what agent causes aspergillosis?
Aspergillus
35
what agent causes cryptococcosis?
Cryptococcus neoformans
36
what agent causes candidiasis?
Candida
37
which agent is the most important fungal agent in terms of numbers of human infections?
Candida
38
what agent causes mucormycosis?
Zygomycetes