Fungi intro Flashcards

1
Q

what type of cells are fungi?

A

eukaryotic

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2
Q

how do fungi reproduce?

A

sexually

asexualy via spores

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3
Q

what are heterotrophs?

A

do not ingest food but parasitize off of living matter

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4
Q

what are the oxygen growth requirements for most fungi?

A

obligate aerobes

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5
Q

what are the oxygen growth requirements for yeast?

A

facultative anaerobes

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6
Q

what is the site of action of most anti-fungal agents?

A

sterols of cell membrane

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7
Q

what differentiates molds?

A

hyphae

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8
Q

what differentiates yeast?

A

budding

mucoid colonies

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9
Q

which form of fungi produces pseudohyphae?

A

yeast (esp. Candida)

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10
Q

what does the germ tube test identify?

A

C. albicans

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11
Q

what mycotic agents are thermally dimorphic?

A

Histoplasma
Blastomyces
Coccidioides
Sporothrix

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12
Q

what type of spores are not encapsulated?

A

Conidia

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13
Q

what size of Conidia is infectious in the RT?

A

Microconidia

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14
Q

what type of spores are thick walled, produced by fragmentation of hyphal cells, and can cause RT infx by inhalation?

A

Arthroconidia

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15
Q

what type of spores are contained within sac-like structures?

A

Sporangiospores

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16
Q

what fungi produce microconidia?

A

Histoplasma
Blastomyces
Aspergillus
Mucormycoses

17
Q

what fungi produce sproangiospores?

A

Coccidioides

PCP

18
Q

if a patient presents with systemic mycosis like symptoms, and a biopsy shows the presence of spherules, what agent is responsible?

A

coccidioidomycoses

19
Q

if a patient presents with systemic mycosis like symptoms, and a CXR shows cysts of 4-6 micrometers in diameter containing intracellular comma-shaped bodies, what agent is responsible?

A

Pneumocystis jiroveci (PCP)

20
Q

what are buds that arise from yeast cells?

A

blastopores

21
Q

what are infections that are confined to the outermost layers of the skin (statum corneum)?

A

superficial mycoses

22
Q

what agents cause superficial mycoses?

A

Malassezia furfur
Piedra hortai
Trichosporon beigelii
Exophiala werneckii

23
Q

what are infections that primarily involve the epidermis, hair, and nails (keratin containing tissue)?

A

cutaneous mycoses

24
Q

what agents cause cutatneous mycoses?

A

Epidermophyton
Microsporum
Trichophyton

25
Q

what special type of cutaneous mycoses is caused by C. albicans?

A

dermatomycosis

26
Q

what are infections that involve skin, subcutaneous tissue, fascia, and bone?

A

subcutaneous mycoses

27
Q

what clinical manifestations present with subcutaneous mycoses?

A

chronic ulcerated lesions with regional lymph node involvement

28
Q

what agents cause subcutaneous mycoses?

A
Sporothrix schenckii
chromomycosis
mycetoma
lobomycosis
phaeomycotic cysts
29
Q

what are the most serious fungal infections that involve internal organs and viscera?

A

systemic mycoses

30
Q

what type of mycoses is caused by a POE of the RT, or sometimes a break in the skin too?

A

systemic mycoses

31
Q

what agents cause systemic mycoses?

A

Blastomyces
Coccidioides
Histoplasma
Cryptococcus

32
Q

what causes opportunistic mycoses?

A

NMF

environmental agents

33
Q

what type of therapy can result in opportunistic mycoses?

A

broad spectrum Abx

34
Q

what agent causes aspergillosis?

A

Aspergillus

35
Q

what agent causes cryptococcosis?

A

Cryptococcus neoformans

36
Q

what agent causes candidiasis?

A

Candida

37
Q

which agent is the most important fungal agent in terms of numbers of human infections?

A

Candida

38
Q

what agent causes mucormycosis?

A

Zygomycetes