Muskoskeletal disorders Flashcards
What are causes of fractures?
Trauma: high or low energy
Stress: abnormal stresses on normal bone
Pathological: normal stresses on abnormal bone
How is soft tissue integrity affected by fractures?
Open- bone has broken through skin
Closed- skin not broken
What are different ways bones can break?
Greenstick- incomplete fracture where bone is bent, occurs most often in children
Simple- fracture of the bone only without damage to surrounding tissues or breaking of skin
Comminuted- bone breaks in several places
How can the displacement of a bone be classified?
Displaced- bone breaks in 2 or more pieces and moves out of alignment
Undisplaced- bone breaks but doesn’t move out of alignment
What causes a stress fracture?
Stress exerted on bone is greater than bone capacity to remodel
Bone weakening leads to stress fracture which can lead to a risk of incomplete fracture
Occurs on weight bearing bone
In what specific type of individual may a stress fracture be common in?
Young female athlete
Females athlete triad: interrelationship between amenorrhea, disordered eating and osteoporosis
What does Wolff’s law tell us about fracture healing?
Bone grows and remodels in response to forces placed upon it
How long does a fracture take to heal?
takes 3-12 weeks depending on site
Signs of visible healing on x-ray from 7-10 days
What are the steps to a fracture healing?
- Inflammation (week 1): haematoma formation, release of cytokines, granulation tissue
- Repair (week 2-4): soft callous formation (type II collagen) converted to hard callous (type I collagen) (1-4 months)
- Remodelling (4-12 months): callous responds to activity, external forces, functional demands and growth. Excess bone is removed
What are pathological disorders that affect bone?
- Osteopenia
- Osteoporosis
- Malignancy
- Vitamin D deficiency (osteomalacia/ rickets)
- Osteomyelitis (bone infection)
- Osteogenesis imperfecta
- Padgets disease
What is osteopenia?
Protein and mineral contents of bone tissue is reduced but less severely than osteoporosis
What is osteoporosis?
Disease characterised by low bone mass and structural deterioration of bone tissue with consequent increase in bone fragility and susceptibility to fracture
Caused by osteoclast activity > osteoblast structure
Most common in females
Secondary osteoporosis can occur at any age. Can be due to hypogonadism, glucocorticoid excess, alcoholism
How do we diagnose osteoporosis and osteopenia?
A t score is used to diagnose- this is standard deviations from the mean using bone mass as unit
T>-1 = normal bone
T -1 - 2.5 = osteopenia
T
how does malignancy cause fractures?
Primary bone cancers inc. : osteosarcoma, chondrosarcoma, Ewing sarcoma, chondroma
Can also get primary tumours in other parts of the body that metastasise to bone inc. prostate, kidney, breast, thyroid and lung
How does vitamin D deficiency cause fractures?
Rickets = paediatric consequence of vitamin D deficiency. Occurs before physis closure. Can cause bowing of tibia/legs Osteomalacia= adult consequence of vit. D deficiency. Occurs after physis closure. Symptoms inc. weaker bones, pain and tenderness