Musculoskeletal Flashcards
What are commonst organisms causing septic arthritis AND what are antibiotics of choice based on age?
Staph Aureus + Streptococcus
<2 yr - Cefotaxime + Flucloxacillin
>2 yr - Flucloxacillin + Ampicillin
What auto-antibodies highly suggestive of SLE?
Anti-DsDNA + ANA
What are the features of systemic juvenile idiopathic arthitis (SJIA)?
Salmon-pink urticarial rash, polyarthritis, lymphadenopathy, hepatosplenomegally
HLA-B27 is associated with what sub-types of JIA?
Enthesitis (inflammation at points of tendon insertion)
Psoriatic
What JIA is most assoicated with elevated ANA and what is the complication you need to look out for?
Oligoarticular JIA (<4 joints involved)
Uveitis
What is first line treatment for developmental dysplasia of hip?
Pavlick Harness
What are the features associated with Osteogenesis imperfecta Type 1?
Recurrent fractures
Blue sclera, hearing loss
What are the features associated with Osteogenesis imperfecta Type 2?
Perinantal + Neonatal fractures
Cardiorespiratory compromise
What are the laboratory findings of vitamin D dependent rickets?
Ca2+- L (initially normal then becomes L)
Po4-L
ALP-H
PTH-H
Vit D- L
What are the laboratory findings of phosphate dependent rickets?
Ca2+ N
Po4- L
ALP H
PTH N/L
Vit D N
What are the clinical features of rickets?
irritability and bone pain, wrist swelling, craniotabes, rachitic rosary, bow legs and proximal muscle weakness.
What are the lab findings for hyperparathyroidism
Ca2+ N/H
Po4- L
PTH H
Vit- H
What are lab findings for seocndary hyperparathyroidism?
Ca2+ L
Po4- L
PTH - H
Vit D- L
What are lab findings of pseudohypoparathyroidism ?
Ca2+ L
Po4- H
PTH - H
Vit D- L
Describe pseudohypoparathyroidism
Genetic disorder
Resistance to PTH
short, LD, short metacarpals
