Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

.pathology > Muscle PP 2 > Flashcards

Muscle PP 2 Flashcards

1
Q

Segmental Regeneration

A

Degenerate segments removed by MOs
Replaced by satellite cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Fibrosis

A

Occurs secondary to significant inflammation, necrosis and hemorrhage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Osseous metaplasia

A

Secondary to hemorrhage
Woven bone production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What does vitamin E/ Selenium deficiency cause in pigs

A

Mulberry heart disease
fast-growing, healthy-looking pigs, affected pigs in nursery phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Eosinophilic myositis (K9)

A

Muscles of mastication
May progress to atrophic myositis
Autoimmune disease targeting type 2 myocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Neosporosis (K9)

A

Neospora caninum
Ingesting infected tissue (aborted calves)
Necropurulent myositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Myasthenia gravis (K9)

A

Generalized muscle weakness
↓ # of ACh receptors at myoneural junction
Maybe megaesophagus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Equine polysaccharide storage myopathy (EPSM)

A

Common genetic defect
Accumulation of polysacc aggregates in type 2 myocytes
Repeated bouts of myodegeneration → m. atrophy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Exertional Rhabdomyolysis other names

A

Azoturia
Monday morning disease
Setfast
Blackwater
Exertional Myopathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

CS of Exertional Rhabdomyolysis

A

Sudden stiff gate, reluctant to move, muscle swelling (gluteal), sweating
↑ CK and AST

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Factors of Exertional Rhabdomyolysis

A

Signs during or immediately after exercise
High grain feeding and lack of regular exercise

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Exertional Rhabdomyolysis pathogenesis

A

Muscle degeneration → myoglobinemia → nephrosis → myoglobinuria → renal failure → acidosis → shock → death

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Forms of Exertional Rhabdomyolysis

A

“Typing up” - less severe form
Paralytic myoglobinuria/ monday morning disease- more severe form

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Lesions of Exertional Rhabdomyolysis

A

Muscles are pale pink or diffusely red-tinged
Hyaline degeneration and necrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Hyperkalemic Periodic Paralysis (HYPP) in horses

A

Genetic disease (one copy of gene)
Muscle twitching and shaking episodes
Quarterhorses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Signs of HYPP

A

Muscle twitching
Shaking
Trembling
Weakness
Collapse

17
Q

HYPP severe signs

A

@ 2-3 years of age
Difficulty swallowing, loud breathing noises
Sudden death (sometimes) after episode

18
Q

Cause of HYPP

A

Mutation in muscles sodium channel
Stress or fasting followed by eating ↑ K (alfalfa)

19
Q

Nutritional Myopathy

A

Vit. E/ Se deficiency in foals
Swollen, pale muscles with polyphasic myodegeneration

20
Q

Seasonal Pasture Myopathy

A

Poisoning with Boxelder seeds (hypoglycin A)
Acute myodegeneration and necrosis

21
Q

Lower Motor neuron disease

A

LMN loss → denervation atrophy of muscles

22
Q

Clostridial myositis (porcine)

A

Wound infection with Clostridia sp.
Serohemorrhagic exudate, necrosis, muscle emphysema

23
Q

Black leg (clostridial myositis)- ruminants

A

Cl. chavoei
Rancid butter smell (butyric acid)
Bruising → tissue destruction (bacterial toxins)

24
Q

Malignant Edema

A

Severe edema
Gas bubbles (crepitus)
Discoloration of overlying skin
Coldness of affected area
Circulatory collapse and death

25
Q

Clostridium Tetanus

A

Wound contamination
Tetanospasmin (exotoxin) → block inhibitory NT in UMN → spastic paralysis

26
Q

Clostridium Botulism

A

Ingestion of spores in GI tract, contaminated wound
Neurotoxin → blocks ACh release in NMJ

27
Q

Myotonia congenita(goats)

A

Thomsen’s disease= fainting goats
Inherited autosomal dominant trait
Affects chloride channels

28
Q

Arthrogyposis

A

Innervation defect
In utero infection/ toxin ingestion → nervous system lesions → failure of innervation of skeletal m.

29
Q

What toxins/ infections cause arthrogyposis

A

Akabane virus, bluetongue virus, poison hemlock, lupine plants

30
Q

Cysticerosis

A

Taenia solium (pork tapeworm)
T. saginata (cow tapeworm)
Zoonotic!

31
Q

Sarcocystosis

A

Affects mammals, birds, reptiles and herbivores (immediate host)
Invade m. fibers (tongue, heart, esophagus)
Zoonotic

32
Q

Gross findings of Sarcocystosis

A

Large # of bradyzoites → cyst grossly visible with nodules, dots or streaks

33
Q

Lipoma

A

Benign tumor of adipocytes in dogs

34
Q

Liposarcoma

A

Malignant lipoma
Infiltrate adjacent soft tissues and muscle

35
Q

Rhabdomyoma/ Rhabdomyosarcoma

A

Tumors that differentiate to form skeletal muscle
Benign and malignant forms

36
Q

Leiomyoma

A

Smooth muscle tumor
Urinary bladder and genetalia

37
Q

Equine melanoma

A

Grey horses
Metastasize to muscle fascia and extend to muscle

38
Q

Hemangiosarcoma

A

Malignant vascular neoplasm arising within muscle
Common in horses and dogs

.pathology (20 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions