MSK: Common Antibodies and Their Disease Associations Flashcards

1
Q

ANA

A

SLE, Nonspecific

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2
Q

Anti-CCP

A

Rheumatoid Arthritis

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3
Q

Anticentromere

A

CREST syndrome

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4
Q

Anti-dsDNA

A

SLE

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5
Q

Antihistone

A

Drug-induced SLE

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6
Q

Anti-Jo-1

A

Polymyositis/dermatomyositis

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7
Q

Antimitochondrial

A

Primary biliary cirrhosis

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8
Q

Antinuclear

A

Scleroderma

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9
Q

Anti-Scl-70

A

Scleroderma

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10
Q

Anti-Sm

A

SLE

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11
Q

Anti-smooth muscle

A

Autoimmune hepatitis

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12
Q

Antitopoisomerase I

A

Scleroderma

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13
Q

Anti-TSHR

A

Graves’ disease

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14
Q

c-ANCA

A

Vasculitis, especially Wegener’s

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15
Q

p-ANCA

A

Vasculitis, microscopic polyangiitis

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16
Q

Rheumatoid factor

A

Rheumatoid Arthritis

17
Q

U1RNP antibody

A

Mixed connective tissue disease