Hematology/Oncology: Disorders Associated with Neoplasms

Question 1

Down syndrome

Answer 1

ALL

Question 2

Xeroderma pigmentosum

Answer 2

Squamous cell and basal cell carcinomas of the skin

Question 3

Chronic atrophic gastritis, pernicious anemia, post-surgical gastric remnants

Answer 3

Gastric adenocarcinoma

Question 4

Tuberous sclerosis (facial angiofibroma, seizures, mental retardation)

Answer 4

Astrocytoma and cardiac rhabdomyoma

Question 5

Actinic keratosis

Answer 5

Squamous cell carcinoma of the skin

Question 6

Barrett’s esophagus (chronic GI reflux)

Answer 6

Esophageal adenocarcinoma

Question 7

Plummer-Vinson syndrome (atrophic glossitis, esophageal webs, anemia–due to iron deficiency)

Answer 7

Squamous cell carcinoma of the esophagus

Question 8

Cirrhosis (alcoholic, HBV, HCV)

Answer 8

Hepatocellular carcinoma

Question 9

Ulcerative colitis

Answer 9

Colonic adenocarcinoma

Question 10

Paget’s disease of bone

Answer 10

Secondary osteosarcoma and fibrosarcoma

Question 11

Immunodeficiency states

Answer 11

Malignant lymphomas

Question 12

AIDS

Answer 12

Aggressive malignant NHLs and Kaposi’s sarcoma

Question 13

Autoimmune diseases

Answer 13

Benign and malignant thymomas

Question 14

Acanthosis nigricans (hyperpigmentation and epidermal thickening)

Answer 14

Visceral malignancy (stomach, lung, breast, uterus)

Question 15

Multiple dysplastic nevi

Answer 15

Malignant melanoma