Common Tumor Markers Flashcards

1
Q

Alkaline phosphatase

A

Metastases to bone, liver, Paget disease of bone, seminoma (placental ALP)

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2
Q

Alpha-fetoprotein

A

HCC, yolk sac tumor, testicular cancer, mixed germ cell tumor (co-secreted with B-hCG)

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3
Q

B-hCG

A

Hydatidiform moles and Choriocarcinomas, testicular cancer

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4
Q

CA 19-9

A

Pancreatic adenocarcinoma

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5
Q

CEA

A

Very nonspecific, but produced by 70% of colorectal and pancreatic cancers

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6
Q

TRAP

A

Hairy cell leukemia

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7
Q

S-100

A

Neural crest origin

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8
Q

CA-125

A

Ovarian Cancer

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9
Q

Calcitonin

A

Medullary thyroid carcinoma

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10
Q

CA-15-3/CA-27-29

A

Breast Cancer

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11
Q

Synaptophysin

A

Neural/neuroendocrine origin

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12
Q

Epithelial membrane antigen

A

Mucin

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