Common Tumor Markers Flashcards
1
Q
Alkaline phosphatase
A
Metastases to bone, liver, Paget disease of bone, seminoma (placental ALP)
2
Q
Alpha-fetoprotein
A
HCC, yolk sac tumor, testicular cancer, mixed germ cell tumor (co-secreted with B-hCG)
3
Q
B-hCG
A
Hydatidiform moles and Choriocarcinomas, testicular cancer
4
Q
CA 19-9
A
Pancreatic adenocarcinoma
5
Q
CEA
A
Very nonspecific, but produced by 70% of colorectal and pancreatic cancers
6
Q
TRAP
A
Hairy cell leukemia
7
Q
S-100
A
Neural crest origin
8
Q
CA-125
A
Ovarian Cancer
9
Q
Calcitonin
A
Medullary thyroid carcinoma
10
Q
CA-15-3/CA-27-29
A
Breast Cancer
11
Q
Synaptophysin
A
Neural/neuroendocrine origin
12
Q
Epithelial membrane antigen
A
Mucin