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MSCT > MSCT Week 5: Acne and Diseases of the Follicle > Flashcards

MSCT Week 5: Acne and Diseases of the Follicle Flashcards

1
Q

Follicle Definition

A

the structure that produces the hair shaft

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2
Q

Basic types of hair shafts

A
  • Vellus hairs
  • Terminal hairs
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3
Q

Question 1

A

~100,000 hair follicles on the scalp

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4
Q

Question 2

A

~100 hairs

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5
Q

Facts about hair

A
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6
Q

Areas of skin without hairs

A
  • Glaborous skin
  • palms and volar surfaces of fingers
  • soles of feet
  • mucosal surfaces
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7
Q

Facts about hair loss

A
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8
Q

hair follicles are immunologically privledged sites

A
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9
Q

Hair follicle cycle of growth

A
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10
Q

Hair follicle cycle

Anagen & Catagen phases

A
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11
Q

Hair follicle cycle

Telogen & Exogen phases

A
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12
Q

Anagen phase

A
  • the production phase of the follicle
  • Estrogens prolong
  • Androgens increase growth rate in more dependent follicles
  • 85-90% of scalp follicles are in this phase at any one time
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13
Q

Catagen Phase

A
  • Regression of follicle
  • less than 1% of scalp follicles at any one time
  • a hair follicle in this phase can spend 2-3 weeks regressing
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14
Q

Telogen Phase

A

Resting phase of follicle

10-15% of scalp follicles at any one time are in this phase

A follicle resting in this phase can retain a hair shaft for up to 3 months

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15
Q

Exogen Phase

A
  • Shedding of the hair shaft
  • actually occurs in early part of anagen phase as the follicle starts to regenerate and grow a new hair shaft
  • Involves not only a mechanical displacement of old hair shaft by new hair shaft but a proteolytic process freeing the shaft from the follicle
  • 100-150 hairs shed per day
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16
Q

Question 3

A

Around 20 cycles per lifetime

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17
Q

Question 4

A

80-85%

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18
Q

Acne epidemiology/associations/long-term effects

A
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19
Q

Acne Who is more likely to get acne?

A
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20
Q

Question 5

A

Blockage of the pilosebaceous unit with keratin debris

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21
Q

Acne Pathogenesis

4 steps

A
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22
Q

Acne Causative agent

A

Propionibacterium acnes

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23
Q

Question 6

A

All of the above

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24
Q

Acne Triggers

6 listed

A
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25
Q

Acne Severity

A
26
Q

Acne types

A
27
Q

Acne Conglobata & Fulminans Descriptions

A
28
Q

Acne Conglobata & Fulminans Treatment

A

Corticosteroids & Isotretinoin

29
Q

Acne Fulminans description

A

Conglobata so severe that it elicits a systemic inflammatory response

Isotretinoin & Corticosteroids

30
Q

Categorizing Acne for Treatment

A
31
Q

Associated Inflammatory Symptoms of Acne

A

PAPA(SH): Pyogenic arthritis, pyoderma, gangrenosum, (cystic) Acne & Hidradenitis Suppuritiva

32
Q

Comedonal Acne Treatment

A
  • Topical Retinoid (BEST)
  • Salicylic Acid
33
Q

Mild Inflammatory or Mixed Acne Treatment

A

Combo topical therapy

  • BP
  • Antibiotic
  • Retinoid
34
Q

Moderate inflammatory or Mixed Treatment

A

Combo Topical Therapy

BP

Antibiotic

Retinoid

+

Oral antibiotic

35
Q

Severe inflammatory or Mixed Treatment

4 listed

A

Combo Topical Therapy

Benzoyl Peroxide

Antibiotic

Retinoid

+

Consider hormonal or isotretinoin

36
Q

Hormonal Acne Treatment

3 listed

A

OCP (oral Contraceptive Pills)

Spironolactone (BP med but blocks androgens)

+/-

Topicals

37
Q

Nodulocystic Acne Treatment

1 listed

A

Isotretinoin

38
Q

Isotretinoin is a

A

Oral retinoid

39
Q

Question 7

A

Topical Retinoid Tretinoin

40
Q

Question 8

A

Topical Antibiotics and or oral antibiotics

41
Q

Treating Acne in Adolescence

A
42
Q

Postinflammatory Dyspigmentation

A
43
Q

Acne Scarring

A
44
Q

Question 9

A

Neonatal cephalic pustulosis (malessezia) Acne mimic

Reassure

No treatment required

45
Q

Infantile and Childhood Acne

Presents as?

Cause?

Scar?

Treat how?

A
46
Q

Childhood Acne

Diagnosis?

Precocious puberty?

How to test?

A
47
Q

Hidradenitis Suppuritiva

A
48
Q

Question 10

A
  • Folliculitis
  • Hot Tub Folliculitis (Pseudomonas)
  • Recent Hot Tub Exposure
49
Q

Folliculitis

A
50
Q

Other Folliculitis Examples

A
51
Q

Question 11

A

80-90%

52
Q

Subtypes of Alopecia

7 listed

A
53
Q

Question 12

A

alopecia areata and Hypothyroidism is related

54
Q

Lichen Planus Pilaris Pathology

A

Scar and destroy hair follicles

55
Q

Alopecia Areata is related to…

A

Hypothyroidism

56
Q

Alopecia Areata

A
57
Q

Alopecia Areata Increases risk for

A
  • autoimmune thyroid problems
  • vitiligo
  • Pernicious Anemia (immune system kills B12 absorbing cells) was fatal before injections
58
Q

Alopecia Areata Scar formation

A

Non-scarring

59
Q

Androgenic Alopecia in men and women

A
60
Q

Trichotillomania

A
61
Q

Question 13

A

Anagen

62
Q

anagen vs telogen effluvium

A

MSCT (30 decks)

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