Morphine

Question 1

Morphine

Class

Answer 1

Narcotic Analgesic

Question 2

Morphine

Description

Answer 2

CNS depressant and a potent analgesic with haemodynamic properties that make it extremely useful in emergency medicine

Question 3

Morphine

Presentation

Answer 3

Ampoule 10mg in 1ml (dilute in 9ml of NaCl)

Supension (10mg/5ml)

Question 4

Morphine

Administration

Answer 4

Intravenous (IV)
Intraosseous (IO)
Orally (PO)
Intramuscular (IM)

Question 5

Morphine

Indication

Answer 5

Adult: Severe Pain (≥ 5 on pain scale)
Paed: Severe Pain (≥ 6 on pain scale)

Question 6

Morphine

Contraindication

Answer 6

PO < 1 Year old
Labour pains
Acute intoxication
Acute respiratory depression
Sys BP < 90mmHg 
KSAR

Question 7

Morphine

Dosage

Answer 7

Adult:
4mg initial dose IV/IO
Repeat 2mg at not < 2 minute intervals if indicated to Max 16mg
For musculoskeletal pain Max 20mg
Up to 10mg IM ( if not cardiac chest pain and no IV access)
Palliative Care: 2.5-5mg SC (rpt x1 ) or 5-10mg PO

Paed: 0.3mg/Kg (300mcg/Kg) PO (Max 10mg)
0.05mg/Kg (50mcg/Kg) IV/IO
Repeat at not < 2 min prn to Max of 0.1mg/Kg IV/IO

Question 8

Morphine

Pharmacology

Answer 8

Opiate Analgesic
Acts on CNS to reduce pain and anxiety
Vasodilation resulting in reduced peload to myocardium

Question 9

Morphine

Side Effects

Answer 9

Respiratory depression
Drowsiness
Nausea & vomiting
Constipation

LTSE - May lead to dependence

Question 10

Morphine

Additional Info

Answer 10

Use with extreme caution particularly with elderly/young
Caution with acute respiratory distress
Caution with reduced GCS
Not recommended for headache
N.B. Controlled under the Misuse of Drugs Act (1977, 1984)