Ceftriaxone

Question 1

Ceftriaxone Class

Answer 1

Antibiotic, Antibacterial

Question 2

Ceftriaxone Descriptions

Answer 2

Antibacterial for Systemic Use

Question 3

Ceftriaxone Presentation

Answer 3

1g Powder for solution for injection

Question 4

Ceftriaxone Administration

Answer 4

IV / IO / IM

IV/IO
Reconstitute each 1g vial in 10ml water for injection. administer over 2-4 mins

IV Infusion
Reconstitute in 100ml NaCl 0.9%. Administer over 30 mins

IM Reconstitute each 1g vial with 3.5ml of 1% Lidocaine and administer by Deep IM injection

Question 5

Ceftriaxone Indications

Answer 5

Severe Sepsis - Adult and Paediatric

Question 6

Ceftriaxone Contra-indications

Answer 6

Age <1 month
KSAR
Hx of Severe Hypersensitivity (anaplylactic reaction) to any Beta-lactam antibacterial (Penicillins, Cephalosporins, Aztreonam, Meropenem, Ertapenem)

Question 7

Ceftriaxone Dose

Answer 7

Adult:
2g IV/IO/IM

Paed:
1 month - 11years: 50mg/kg IV/IO/IM
>11years or >50Kg: 2g IV/IO/IM

Question 8

Ceftriaxone Pharmacology/Action

Answer 8

Antibacterial Spectrum

Question 9

Ceftriaxone Side Effects

Answer 9

Diarrhoeaa
Rash
Headache
Dizziness
Nausea
Vomiting
Pruritis

Question 10

Ceftriaxone Additional Info

Answer 10

DO NOT MIX with or administer simultaneously with any Calcium-containing intravenous solutions
Preferred route is IV Infusion
Lidocaine only to be used with IM route