Mag Sulphate Flashcards
Magnesium Sulphate Injection
Class
Electrolyte and Tocolytic agent
Magnesium Sulphate Injection
Description
It is a salt that is an essential element in numerous biochemical reactions that occur within the body
Magnesium Sulphate Injection
Presentation
5g in 10mL ampoule
Magnesium Sulphate Injection
Administration
Intravenous (IV)
Intraosseous (IO)
Magnesium Sulphate Injection
Indications
Life Threatening Asthma
Torsades de pointes
Persistent Bronchospasm
Seizure associated with eclampsia
Magnesium Sulphate Injection
Contraindications
None in cardiac arrest
KSAR
Magnesium Sulphate Injection
Dosage
Adult:
Life Threatening Asthma: 2g IV Infusion over 20 mins
Torsades (with pulse): 2g IV infusion over 15 minutes
Bronchospasm: 2g IV infusion over 20 minutes
Seizure with Eclampsia: 4g IV infusion over 15 mins
Paed: not indicated
Magnesium Sulphate Injection
Pharmacology
It acts as a physiological calcium channel blocker and blocks neuromuscular transmission
Magnesium Sulphate Injection
Side Effects
Bradycardia (during infusion, give slowly) Arrhythmias Coma Confusion Drowsiness Flushing of skin Hypotension Decreased deep tendon reflexes, Muscle Weakness Nausea and Vomiting Respiratory depression, Thirst
Magnesium Sulphate Injection
Additional Info
Dilute in 100mL NaCl for infusion
5g in 10ml is equivalent to 20mmol/mg