GTN

Question 1

GTN

Class

Answer 1

Nitrate

Question 2

GTN

Description

Answer 2

Special preparation of Glyceryl Trinitrate in an aerosol form that delivers precisely 0.4mg of GTN per spray

Question 3

GTN

Presentation

Answer 3

Aerosol spray: metered dose 0.4mg (400mcg)

Question 4

GTN

Administration

Answer 4

Sublingual (SL)

Question 5

GTN

Indications

Answer 5

Angina
Suspected Myocardial Infarction (MI)
Pulmonary Oedema

Question 6

GTN

Contraindications

Answer 6

Sys BP <90 mmHg
Viagra or other Phosphodiesterase type 5 inhibitors (sildenafil,taladafil, vardenafil) used within previous 24 hours
Severe Mitral Stenosis
KSAR

Question 7

GTN

Dosage

Answer 7

Adult:
Angina or MI: 0.4mg repeat at 3-5 mins to max 1.2mg
Pulmonary Oedema: 0.8mg Repeat X 1

Paed: not indicated

Question 8

GTN

Pharmacology

Answer 8

Vasodilator
Releases nitric oxide which acts as a vasodilator.
Dilates coronary arteries particularly if in spasm, increasing blood flow to the myocardium.
Dilates systemic veins reducing venous return to the heart (preload) and thus reduces the heart workload.
Reduces BP.

Question 9

GTN

Side Effects

Answer 9

Headache
Transient Hypotension
Flushing
Dizziness

Question 10

GTN

Additional Info

Answer 10

Caution with inferior wall MI with Right Ventricular Involvement as this may lead to profound hypotension
If the pump is new or has not been used for a week or more the first spray should be released into the air