Epinephrine 1:1,000

Question 1

Epinephrine 1:1,000 Class

Answer 1

Sympathetic Agonist

Question 2

Epinephrine 1:1,000 Description

Answer 2

Naturally occurring catecholamine.
It is a potent alpha and beta adrenergic stimulant;
however, its effect on beta-receptors is more profound

Question 3

Epinephrine 1:1,000 Presentation

Answer 3

Pre-filled syringe, ampoule or auto injector1mg/ml (1:1,000)

Question 4

Epinephrine 1:1,000 Administration

Answer 4

Intramuscular (IM)
Intravenous (IV)
Intraosseous (IO)
Nebulised (Neb)

Question 5

Epinephrine 1:1,000 Indications

Answer 5

Severe Anaphylaxis
Stridor
Symptomatic Bradycardia
Cardiogenic Shock

Question 6

Epinephrine 1:1,000 Contraindications

Answer 6

None known

Question 7

Epinephrine 1:1,000 Dosages

Answer 7

Adult:0.5mg (500mcg) (1:1,000) IM
Repeat every 3-5 mins if indicated

Adult: Symptomatic Bradycardia / Cardiogenic Shock
0.01mg IV/IO Repeat PRN

Paed: >8yrs - 0.5mg (500mcg) (.5ml)repeat every 3-5 mins if indicated
6 - 8 yrs - 0.25mg (250mcg) (.25ml)repeat every 3-5 mins if indicated
6 mths - 5 yrs - 0.125mg (125mcg) (.13ml)repeat every 3-5 mins if indicated
< 6 mths - 0.05mg (50mcg) (.05ml)repeat every 3-5 mins if indicated

Paed Stridor:
<1 year 2.5mg Neb
≥ 1 year 5mg Neb
(Rpt x1 @30 mins if required)

Question 8

Epinephrine 1:1,000 Pharmacology

Answer 8

Alpha and beta adrenergic stimulant.
Reversal of laryngeal oedema and bronchospasm in anaphylaxis.
Antagonises effects of histamine

Question 9

Epinephrine 1:1,000 Side Effects

Answer 9

Palpitations
Angina like symptoms
Tachyarrhythmias
Hypertension

Question 10

Epinephrine 1:1,000 Additional Info

Answer 10

N.B. Double check the concentration on pack before use