Module 7: Pathophysiology of Common Diseases and Conditions Flashcards
1
Q
Diabetes mellitus type 1
A
- endocrine system
- unknown cause (possibly autoimmune, genetic, or environmental)
- polyuria, polydipsia, fatigue, blurry vision, weight loss, elevated blood glucose
- insulin therapy
2
Q
Diabetes mellitus type 2
A
- endocrine system
- obesity, inactivity, genetics
- polyuria, polydipsia, fatigue, elevated blood glucose
- diet modification, exercise, medication, insulin therapy
3
Q
Polycystic ovary syndrome (PCOS)
A
- endocrine system
- unknown causes (possibly genetic, excessive insulin)
- irregular menstrual cycles, elevated hormone levels, multiple cysts on ovaries
- weight loss, estrogen and progestin
4
Q
Hypothyroidism
A
- endocrine system
- autoimmune disease, medications, thyroid surgery
- fatigue, weight gain, muscle aches, bradycardia, depression, elevated cholesterol, dry skin
- synthetic thyroid hormone medication (levothyroxine)
5
Q
Hyperthyroidism
A
- endocrine system
- Graves disease, thyroiditis, Plummers disease
- weight loss, tachycardia, anxiety, fatigue, sleep disruption, goiter
- radioactive iodine, antithyroid medication, beta blockers, thyroidectomy
6
Q
Basal cell carcinoma (BCC)
A
- integumentary system
- light/fair skin, sun exposure
- new growth/sore that does not heal
- curettage and electrodesiccation, Mohs surgery, cryosurgery, laser therapy
7
Q
Squamous cell carcinoma
A
- integumentary system
- light/fair skin, sun exposure, less common than BCC
- spreads to surrounding tissue, most common on the face and head
- curettage and electrodesiccation, Mohs surgery, cryosurgery, laser therapy
8
Q
Malignant melanoma
A
- integumentary system
- light/fair skin, sun exposure
- itchy/bleeding mole, new mole, mole with changes
- depends on stage of lesion, surgery, lymph node biopsy, chemotherapy, radiation therapy, immunotherapy
9
Q
Acne vulgaris
A
- integumentary system
- surge of sex hormones during puberty, excess sebum on skin surface
- black heads/white heads (comedones), papules/pustules
- regular cleansing of affected area, OTC benzoyl peroxide products, prescription medication (topical or oral)
10
Q
Alopecia
A
- integumentary system
- often hereditary, hormone changes, chemotherapy, stress, burns, fungal skin infections
- loss or lack of hair anywhere on the body (typically on the scalp), can include eyebrows and eyelashes
- no cure, hair transplants and medications can slow progression
11
Q
Cellulitis
A
- integumentary system
- staphylococcal and streptococcal bacterial infections
- red and tight skin, pain in inflamed area, fever
- oral/topical antibiotics, hospitalization if at risk for developing systemic infections
12
Q
Dermatitis
A
- integumentary system
- multiple causative agents, contact with irritants
- inflammation of skin resulting in rash and pruritus
- based on cause, corticosteroid creams, oral steroids
13
Q
Eczema
A
- integumentary system
- unknown causes (possible allergy or inflammatory condition)
- chronic dermatitis with vesicular eruptions developing into itchy/red/scaly rash
- topical or systemic steroids, NSAIDs for discomfort
14
Q
Folliculitis
A
- integumentary system
- shaving or repeated rubbing of shaved area, bacteria or fungi
- red and itchy hair follicles (pimple appearance)
- regular cleansing of affected area, topical antibiotics, electric shaver instead of razor
15
Q
Herpes simplex
A
- integumentary system
- contact with herpes simplex virus
- Type 1: painful blisters on lips/mouth/face
- Type 2: similar lesions, located in genital area
- no cure, antiviral medication to decrease frequency of outbreaks
16
Q
Impetigo
A
- integumentary system
- staphylococcal and streptococcal bacteria
- itchy and oozing skin lesions with honey-like appearing crust
- antibiotics, frequent cleaning of area
17
Q
Pediculosis
A
- integumentary system
- parasitic lice infestation
- skin itching, nits (eggs) in hair near roots
- prescription or OTC lice treatments/shampoos
18
Q
Psoriasis
A
- integumentary system
- inherited autoimmune disorder
- silvery/scaly/severely itchy skin lesions, can cause systemic symptoms such as joint pain and inflammation (psoriatic arthritis)
- oral NSAIDs, topical creams containing vitamins A and D, hydrocortisone cream, UV treatments
19
Q
Ringworm
A
- integumentary system
- contact with causative fungus
- flat and circular lesions (dry/scaly or moist/crusty)
- topical and oral antifungal medication
20
Q
Rosacea
A
- integumentary system
- dilation of small facial blood vessels, cause of dilation is unknown
- redness, acne-like eruptions on face
- topical cortisones, antibiotics, vascular laser therapy
21
Q
Osteoarthritis
A
- musculoskeletal system
- inflammatory processes, metabolic disorders
- joint stiffness and pain, fluid surrounding the joint, grating sound with joint movement
- NSAIDs, intra-articular injections, arthroscopy, joint replacement surgery
22
Q
Rheumatoid arthritis
A
- musculoskeletal system
- autoimmune
- destruction of the joint capsule causing scar tissue to form, visible joint deformity, loss of joint mobility
- NSAIDs, exercise, heat and cold therapies, cortisone injections, surgery to remove scar tissue
23
Q
Bursitis
A
- musculoskeletal system
- overuse, joint trauma, bacterial infection
- joint pain and swelling
- rest, pain medication, steroid injection, aspiration of joint fluid, antibiotics
24
Q
Ewing’s Sarcoma
A
- musculoskeletal system
- unknown causes, age 10-20, male sex
- fever, pain at tumor sight, fractures, bruising
- surgery, chemotherapy, radiation therapy, bone marrow transplant, stem cell transplant
25
Q
Gout
A
- musculoskeletal system
- deposits of uric acid crystals accumulate in joint spaces
- joint pain, common in big toe and knee joints, stiffness, swelling
- dietary changes (avoidance of rich/fatty foods), pain medication, medications to aid in elimination of uric acid in kidneys during urine formation
26
Q
Kyphosis
A
- musculoskeletal system
- growth retardation or improper development of growth plates, aging and degenerative disk disease contribute to adult-onset
- visible upper back curvature (humpback)
- exercise, back bracing, Harrington rod, spinal fusion in extreme cases
27
Q
Lordosis
A
- musculoskeletal system
- injury, poor posture, wearing high heels (inward positioning of back when balancing on balls of feet)
- inward curvature of the lower back (swayback)
- corrective shoes, exercise
28
Q
Osteogenesis imperfecta (brittle bone disease)
A
- musculoskeletal system
- hereditary
- dental issues, fractures at birth, loose joints, muscle weakness, respiratory issues, blue sclera of the eye, triangle-shaped face, small stature, spinal curvature
- fracture repair, surgery with metal rodding, physical therapy, bracing
29
Q
Osteoporosis
A
- musculoskeletal system
- hormone deficiencies, sedentary lifestyle, lack of vitamin D, corticosteroid use (long-term), smoking
- fractures, most common in spine/wrists/hips, loss of height, can result in kyphosis
- medications, hormone replacement therapy, exercise, supplements
30
Q
Osteosarcoma
A
- musculoskeletal system
- unknown
- pain in affected bones (usually legs), swelling with development of tumor growth
- surgery, chemotherapy/radiation, amputation of affected limb
31
Q
Paget’s disease
A
- musculoskeletal system
- hereditary, viral
- bone pain and deformity, fractures, excessive bone destruction
- surgery, medication, physical therapy
32
Q
Scoliosis
A
- musculoskeletal system
- possibly genetic, can be prenatally during formation of vertebrae, muscle weakness
- bent appearing spine (laterally), back pain
- back bracing, physical therapy, surgery with rod placement
33
Q
Fibromyalgia
A
- musculoskeletal system
- unknown, exacerbated by sleep deprivation/emotional distress/depression
- fatigue, point tenderness and trigger points, chronic facial pain, sleep disturbances
- antidepressants, NSAIDs, physical therapy, trigger point injections
34
Q
Muscular dystrophy
A
- musculoskeletal system
- hereditary
- muscle weakness leading to eventual paralysis of muscle groups
- physical therapy, bracing, ambulatory devices, medications
35
Q
Myasthenia gravis
A
- musculoskeletal system
- autoimmune
- double vision, muscle weakness, dysphagia, difficulty swallowing, difficulty chewing
- avoiding excessive stress, rest, eye patch, medication
36
Q
Tendonitis
A
- musculoskeletal system
- sports or activity related
- pain in joints, limited range of motion in joint
- rest, ice, NSAIDs
37
Q
Tetanus
A
- musculoskeletal system
- toxin produced by Clostridium tetani
- muscle spasms in jaw and neck, dyspnea, fever, irritability, sweating and drooling
- antitoxin and antibiotic medications
38
Q
Asthma
A
- respiratory system
- allergens, pollutants, dust mites, cigarette smoke
- wheezing, coughing, feeling of tightness in chest
- avoiding allergens/irritants, rescue inhaler for bronchodilation, anti-inflammatory steroid inhalers, leukotriene-receptor antagonists, steroid injection for an acute episode
39
Q
Atelectasis
A
- respiratory system
- cystic fibrosis, COPD, pleurisy, lung cancer, spontaneous
- dyspnea, cyanosis, diaphoresis, pain
- thoracentesis, chest percussion, deep breathing exercises, intermittent positive-pressure breathing
40
Q
Bronchitis
A
- respiratory system
- viral, environmental pollutants, cigarette smoke
- yellow-gray or green productive cough, chest tightness, dyspnea, fever
- cough medicine, humidifier, inhalers, antibiotics in some cases