Module 12 Exam 2 Flashcards

1
Q

What is diabetes mellius

A

a group of metabolic diseases characterized by hyperglycemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what does hyperglycemia result from

A

and insulin deficiency, resistance to insulin or both

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is chronic hyperglycemia associated with

A

long term damage, dysfunction, and failure of numerous organs, especially the eyes, kidneys, nerves heart, and blood vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what becomes more prevalent as the population ages and obesity increases

A

diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is insulin

A

a hormone produced by the beta cells in the pancreas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what does insulin effect

A

it directly or indirectly effects every organ in the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what does insulin enable

A

glucose transport into cells to use as energy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what are the main functions of insulin

A
  • facilitates glucose uptake from blood into tissues
  • speeds oxidation of glucose within cells for energy
  • speeds conversion of glucose to glycogen to store in the muscles to prevent it converting back to glucose
  • conversion of glucose to fat in adipose tissue
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what are normal blood glucose levels in healthy individuals

A

60-150 mg/dl

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what happens with the increased glucose in the blood in type 1 diabetes

A

it spills over into the urine, causes excretion of large amts of urine, causes water and electrolyte loss, which signals thirst in the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What may cells in Type 1 diabetes starving for glucose cause the patient to do

A

increase food intake, but weight loss may still occur

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Without glucose for energy in Type 1 was does the body do for energy

A

metabolizes fat for energy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what does the metabolism of fat end in

A

harmful ketones that accumulate in the blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what are ketones

A

when in large quantity body cant handle and it causes metabolic acidosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what can metabolic acidosis lead to

A

a diabetic coma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

does the insulin production and secretion by the pancreas remain at normal levels in type 2 diabetes

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what happens in type 2 diabetes

A

-insulin receptors develop defects and glucose cant be transmitted to the cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what level increases as the insulin resistance of the cells increase

A

blood glucose levels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is hypoglycemia/insulin shock

A

-too much insulin which lowers level of blood glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

what is the more common emergency likely to occur in the dental setting, hyper or hypo

A

hypoglycemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

what is hyperglycemic reaction/ diabetic coma (ketoacidosis)

A

too little insulin, increased levels of blood glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is type 1 diabetes

A

-absolute insulin deficency resulting from the destruction of the insulin-producing beta cells in the pancreas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

When does type 1 diabetes usually arise

A

childhood or puberty

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what are former names of type 1 diabetes

A

-insulin dependent diabetes mellitus, juvenile diabetes, juvenile onset, ketosis-prone diabetes, brittle diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
what is type 2 diabetes
pancreatic insulin secretion may be low, normal, or even higher than normal but the patient exhibits an insulin resistance that impairs the use of insulin
26
what is gestational diabetes mellitus
any degree of glucose intolerance with onset or first recognition during pregnancy
27
what is gestational diabetes related to
genetics, obesity, hormones
28
when is gestational diabetes diagnosis reclassified
6 weeks after pregnancy ends
29
what has lessened the danger of gestational diabetes for the mother
insulin adjustment, carefully supervised prenatal care, improved obstetrics
30
What are characteristics of the pregnancy and baby in a mother with gestational diabetes
- larger infant - premature births more freq - congential malformations, perinatal death - tendency to develop type 2 diabetes later in life
31
What do other types of diabetes result from
-genetic defects, diseases, endocrinopathies, surgery, drugs, malnutrition, infections, injury
32
what are some genetic defects that cause diabetes
- genetic defects of the beta cell, or insulin action
33
what are some diseases of the exocrine pancreas that cause diabetes
- diseases that injure or destroy beta cells | - pancreatitis, trauma, pancreatectomy, carcinoma, cystic fibrosis
34
what are endocinopathies that cause diabetes
- HGH, cortisol, glucagons, epi antagonize insulin action | - acromegaly, cushing syndrome, hyperthyroidism
35
what do drugs or chemicals do to induce diabetes
- chemicals impair insulin secretion, insulin action, destroy betal cells - glucocorticoids, thyroid hormone, dilantin, thiazides
36
what do infections do to cause diabetes-
- viruses can destroy beta cells | - congenital rubella, cytomegalovirus, mumps
37
what are some syndromes associated with diabetes
- down sydrome - huntingtons disease - prader willi syndrome
38
what are symptoms of hyperglycemia
``` polyuria polydypsia weight loss polyphagia blurred vision increased susceptibility to infections impaired growth ```
39
to diagnose diabetes what should the a1c number be over
6.5%
40
to diagnose diabetes what is the fasting glucose over
126 mg/dl
41
to diagnose diabetes what is the 2 hour plasma glucose greater than
200 mg/dl
42
What are the complications of diabetes relating to infections
-patients are more susceptible to infections -failure to treat intensifies symptoms of diabetes -
43
what may cause insulin requirements to increase
fever, infection, inflammation, trauma, bleeding, pain, or stress
44
What is peripherial neuropathy
- pain, numbness, or tingling of mouth, face and extremities | - leads to increased incidence of amputations because of delayed ID of problems
45
what is autonomic neuropathy
- can cause GI symptoms | - food is delayed in stomach, leading to a delay in adsorbtion, and complications managing blood glucose
46
what is nephropathy
- diabetes is the leading cause of renal disease, and most common of end stage renal disease - dialysis or kidney transplant may be needed
47
what is retinopathy
- diabetes is leading cause of blindness | - patients are more likely to have glaucoma and cataracts
48
what are the complications of diabetes and cardiovascular disease
-heart disease -peripherial vascular disease -cerebrovascular disease -hypertension may lead to myocardial infarction and stroke
49
what is a major cause of limb amputation
diabetes
50
pregnant patients who have diabetes are at a higher risk for
spontaneous abortion, miscarriages, babies with birth defects, increased weight
51
What are the psychosocial problems of diabetes
-tx regimens challenging to cope with, lead to emotional and social problems, including depression
52
Diabetes is known as
the silent killer
53
what does diabetes reduce
average life span, diabetes and its complications are leading causes of death
54
what are the general procedures for someone who has diabetes
- early diagnosis - education for self care - maintain best overall health - maintain tight glycemic control - immediate tx for acute symptoms
55
What is an essential part of the tx program which lowers insulin requirements, cardiovascular risk factors
exercise
56
what can many cases of type 2 diabetes be controlled with
weight reduction and exercise alon
57
what are goals of medical nutritional therapy
prevent and manage diabetes and slow the development of complications
58
what are the fundamentals of the diet for a diabetic
-high fiber, low fat, low cholesterol, low sodium
59
What should we know about tobacco use and diabetes
- pt must avoid all types of tobacco | - increases risk of heart disease, stroke, MI, limb amputations, perio disease, numerous health problems
60
Why should diabetic pts avoid excess alcohol?
-can raise blood pressure and contribute to other health problems
61
Do type 1 and type 2 require exogenous insulin?
yes- type 1 for survival and type 2 for control
62
What are the different types of insulin
-rapid, short, intermediate, or long acting based on the onset, peak and duration of action
63
what does the dosage of insulin depend on
-the individual
64
what factors affect the need for insulin
-food intake, illness, stress, variations in exercise, infections
65
what are the methods for insulin administration
- insulin pen - sub Q injection with syringe - continuous sub Q insulin infusion with a battery operated insulin pump - inhalable insulin
66
what are oral hypoglycemic medications used to treat
type 2 in conjunction with diet, exercise, and possibly injection of insulin
67
what has pancrease transplantation eliminated the need for
exogenous insulin in type 1 patients
68
What findings in the gingva occur with diabetes
increased gingival inflammation
69
what findings with the periodontium occur in diabetes
- periodontitis - attachment loss - deep pockets - alveolar bone loss - tooth mobility and migration - healing delayed
70
what findings with teeth occur in diabetes
- increased risk of caries related to decreased saliva, diet in poorly controlle diabetes - in well controlled: caries related to low sugar, regular habits, maintenance
71
what findings with the lips occur in diabetes
-dry, cracking, angular chelitis
72
what findings with the saliva occur in diabetes
- decreased flow - glucose in sulcular fluid - xerostomia
73
what findings with the mucosa occur in diabetes
- edematous, red - candidiasis - burning mouth or tongue - delayed healing - increase lichen planus,
74
what findings with taste occur in diabetes
-hypogeusia, diminished taste perception
75
Perio infections may also affect control of blood glucose by increasing what
insulin resistance in a manner similar to obesity
76
patients with uncontrolled glucose levels have more severe what
perio disease at younger ages
77
diabetes does not cause oral disease but may lower what and increase what
resistance and susceptibility to oral findings
78
what can affect blood sugar levels during a dental appointment
stress
79
When is antibiotic premedication indicated
routine dental tx is deferred until diabetes is stabilized, consult for premed
80
What time should you treat a patient
- treat on a full stomach - avoid peak insulin level - ideal time varies with each patient
81
what precautions should be taken in a patient with diabetes
- dont keep waiting - dont interfere with regular meal - avoid long stressful procedures - prevent and treat all infections - prep. for diabetic emergencies
82
what is diabetes insipidus
a rare disease characterized by polyuria, polysdipsia indued by antidiuretic hormone defect