Mod 2- Digestive Tract Glands

Question 1

what is the main cell of the liver that is responsible for formation of exocrine and endocrine products

Answer 1

Hepatocyte

Question 2

what is the blood supply of the liver (%) and where does it leave

Answer 2

Hepatic arteries 25%
Portal vein 75%

enter thru ports hepatic and leaves thru portal veins

Question 3

what does bile travel thru to leave the liver

Answer 3

porta hepatis by way of hepatic ducts

Question 4

How are hepatocytes organized

Answer 4

form hexagon shaped classic lobules with central vein in middle

Question 5

What is it called in the area where 3 classic lobules meet and what is found there

Answer 5

Portal area

• hepatic artery
• tributaries of portal vein
• iterlobular bile ducts
• lymph vessels

Question 6

what is the hepatic lobule

Answer 6

triangle area of three classic lobule where all the bile excreted goes into the bile duct

Question 7

what are the 2 domains of a hepatocyte

Answer 7

Lat domains- intercellular space and have bile canaliculi

Sinusoidal domains- have microvilli that facilitate exchange of materials

Question 8

main function of hepatocyte

Answer 8

• manufacture primary bile
• synthesize enzymes
• store vitamins
• detoxification

Question 9

what are Kupffer cells and where are they found

Answer 9

• Derived from monocytes located in the hepatic sinusoids

- phagocytose foreign particles

Question 10

What are the excretory components of the pancreas

Answer 10

islets of Langerhans (scattered among acini)

Question 11

What are the 5 cell types in the islets of langerhans

Answer 11

• alpha cells
• beta cells
• PP cells
• G cells
• delta cells

Question 12

what are the 3 endscrine glands of the pancreas

Answer 12

Beta cells 75%- insulin

Alpha cells 20%- glucagon

delta cells 5%- somatostitin

Question 13

Diff between type 1 and 2 diabetes

Answer 13

1- auto immune disorder where insulin producing cells destroyed

2- insulin resistance (needs more than usual)