Midazolam Flashcards

1
Q

Midazolam - Type

A

Anticonvulsant and sedative agent

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2
Q

Midazolam - Presentation

A

5mg in 5ml

15mg in 3ml

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3
Q

Midazolam - Actions (3)

A
  1. Anticonvulsant - reduces seizure activity
  2. Minor tranquilliser
  3. Muscle relaxant
    IV onset 1-5 min, duration 2-3 hrs
    IM onset 2-5 min, duration 2-3 hrs
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4
Q

Midazolam - Uses (4)

A
  1. Status epileptics - in a pt who has continual or prolonged seizures
  2. Mild sedation to permit basic airway management
  3. Adjunct to analgesia for injuries where significant muscle spams is present
  4. To manage agitated and combative pt
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5
Q

Midazolam - Adverse effects (3)

A

Depression of level of consciousness, leading to:

  1. Respiratory depression
  2. Loss of airway control
  3. Hypotension
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6
Q

Midazolam - Contraindication

A

Known hypersensitivity

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7
Q

Midazolam - Precautions (2)

A
  1. Haemodynamic instability

2. Respiratory depression

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8
Q

Midazolam - Doses

A

Seizures
- Adult & Paediatric - 0.1mg/kg IM/IV no max, IV over 2/60

Adjunct to analgesic use with muscle spasm

  • Adult and Paediatric - up to 0.05mg/kg IV over 2/60
  • rep x 1 as req
  • after 1 dose methoxy or 2 doses morphine

Mild sedation to facilitate basic airway management
- Adult and Paediatric - 0.1mg/kg over 2 mins

Post intubation sedation as adjunct to ketamine
- Adult and Paediatric - 0.05mg/kg IV

When used to manage a combative or agitated pt
- Adult and paediatric - up to 0.1mg/kg until manageable.
- may repeat as req to continue management, IV/IM
If agitation and combativeness due to psychostimulant
- up to 0.2mg/kg IM/IV until manageable
All agitated pt management doses may be reduced
- if there is known or suspected hypotension or hypovolaemia
- in frail or elderly pts
- for pts with general debility

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