Metoclopramide

Question 1

Metoclopramide - Type

Answer 1

Antiemetic

Question 2

Metoclopramide - Presentation

Answer 2

10mg in 2ml

Question 3

Metoclopramide - Actions (2)

Answer 3

1. Antiemetic, centrally acting on the brain stem
2. Increases gastric emptying
   Onset IV 3-15 min, duration 30min

Question 4

Metoclopramide - Use (2)

Answer 4

1. Prevent vomiting
   - when narcotic analgesic is to be administered
   - high spinal injury
   - serious eye injury
   - suspected ischaemic chest pain
2. Treat nausea and vomiting

Question 5

Metoclopramide - Adverse effects (5)

Answer 5

Uncommon with usual doses, occasionally:
1.  Drowsiness
2. Lethargy
3. Dry mouth
4. Oculogyric crisis, facial spams
5. Speech difficulties
Side effects may be more common in dehydrated adolescents

Question 6

Metoclopramide - Contraindications (2)

Answer 6

1. Previous reaction

2. GI bleeding

Question 7

Metoclopramide - Precaution

Answer 7

Concomitant phenothiazine use will increase likelihood of side effects.

Question 8

Metoclopramide - Dose

Answer 8

Adult - 10mg (over 2 mins if IV)
Single dose only
Give prior to narcotic administration