Lignocaine

Question 1

Lignocaine - Type (2)

Answer 1

1. Local anaesthetic

2. Anti-arrhythmic

Question 2

Lignocaine - Presentation

Answer 2

50mg in 5ml

Question 3

Lignocaine - Actions (2)

Answer 3

1. Local anaesthetic effects
2. Suppresses ventricular arrhythmias
   SCI Onset 1-4 mins, max 5-10 mins
   IV Onset 1-3 mins

Question 4

Lignocaine - Uses (3)

Answer 4

1. Local anaesthesia prior to invasive procedures
2. VT with cardiac output in pts who cannot have amiodarone
3. Flushing of a painful IO in an aware pt

Question 5

Lignocaine - Adverse effects (2)

Answer 5

Extremely unlikely in usual subcutaneous doses. More likely in IV.

1. CNS effects: stimulation followed by depression, drowsiness, agitation, muscle twitching, seizures, coma
2. Cardiac effects: hypotension, bradycardia, heart block, asystole

Question 6

Lignocaine - Contraindication

Answer 6

Known hypersensitivity

Question 7

Lignocaine - Dose (IO in aware pt)

Answer 7

Volume of 10mg/ml
Neonate (3-4kg) - 0.2ml
0-1 yr (4-11kg) - 0.3ml
1-5 yr (11-19kg) - 0.7ml 
5-12 yr (19-36kg) - 1.5ml
12+ yr (35+ kg) - 3ml
Adult (80+ kg) - 4ml
Subsequent dose as ½ of initial dose

Question 8

Lignocaine - Dose (local anaesthesia and VT with CO)

Answer 8

Local anaesthesia
Adult & Paediatric - up to 5ml s/c

VT with CO
Adult & Paediatric - 1mg/kg IV over 2mins