Micro - CNS infections + meningitis

Question 1

4 processes involved in septicaemia (the 2Cs and 2Ms)

Answer 1

Capillary leak
Coagulopathy
Myocardial failure –> organ hypo perfusion
METABOLIC derangement

Question 2

2 most common causes of “aseptic meningitis”

Answer 2

Coxsackie group B

Echoviruses

Question 3

Viral causes of encephalitis

Answer 3

HSV
MMR
VZV
west nile

Question 4

1 bacterial cause of encephalitis

Answer 4

Listeria monocytogenes

Question 5

1 organism which causes severe infection in the immunocompromised and can cause encephalitis?

Answer 5

Toxoplasmosis

Question 6

3 routes of infection for spinal infection?

Answer 6

Haematogenous spread
Direct spinal trauma
Adjacent structures

Question 7

which imaging modality is best for visualising parenchymal abnormalities?

Answer 7

MRI

Question 8

3 sites of culture which are useful for ?CNS infection?

Answer 8

Blood
CSF
Nasal swab

Question 9

CSF results in TB meningitis

Answer 9

High lymphocytes
Low glucose
High protein

Question 10

CSF results in viral meningitis

Answer 10

High lymphocytes
Norm glucose
Norm protein

Question 11

appearance of CSF in TB meningitis

Answer 11

fibrinous

Question 12

empirical antibiotics in an adult with suspected meningitis

Answer 12

ceftriaxone + amoxicillin

Question 13

Rich focus?

Answer 13

cerebral TB, where there is rupture of a TB granuloma

Question 14

Gold standard test for leptospirosis

Answer 14

microscopic agglutination test

Question 15

Cryptococcus noeformans- what type of organism is it?

Where does it come fro,m?

Answer 15

Fungus

Pigeon droppings

Question 16

India ink test

Answer 16

Cryptococcus neoformans

Question 17

Gram +, alpha haemolytic diplococcus

Answer 17

Strep pneumonia