histopath - cerebrovascular path Flashcards
Define stroke
> 24hours
- focal/global loss of cerebral function
- inadequate vascular perfusion
Most common site for cerebral thrombosis
- Carotid bifurcation
2. Basilar artery
Most common site for cerebral embolus
Middle cerebral artery
Typical site of embolism in TIA?
ophthalmic branch of internal carotid
Ix in TIA to attempt to confirm Dx?
Carotid USS
Initial management of TIA
Aspirin + dipyridamole +/- carotid endarterectomy
If <3h since stroke, what is the management
thrombolytics + aspirin +/- dipyridamole
Cause of global cerebral ischemia
Failure of systemic circulation eg HF
3 non-traumatic forms of cerebral haemorrhage?
- Intraparenchymal haemorrhage
- Subarachnoid haemorrhage
- Arteriovenous malformations
Main RF for intraparenchymal haemorrhage
Hypertension
Most common site of intraparenchymal haemorrhage
Basal Ganglia
RFs for subarachnoid haemorrhage
PCKD
Ehlers Danlos
Aortic Coarctation
Most common cause + site of subarachnoid haemorrhage
Carotid bifurcation
Tx of subarachnoid haemorrhage from rupture berry aneurysms?
coil - stops blood flow through weak vessel area
coup
where impact occurs