Micro Flashcards
What are the 7 urease positive organisms
Proteus Cryptococcus H. pylori Ureaplasma Nocardia Klebsiella S. epidermidis S. saprophyticus
“P CHUNKSS”
Urease positive organisms predispose to
struvite stones
What are the 3 obligate intracellular bacteria
Rickettsia
Chlamydia
Coxiella
Rely on host ATP
What are the 7 facultative intracellular bacteria
Salmonella Neisseria Brucella Mycobacterium Listeria Francisella Legionella Yersinia perstis
What are the 4 anaerobic bacteria
Clostridium
Bacteroides
Fusobacterium
Actinomyces israeli
normal in the GI tract
Why can’t ahminoglycosides work on anaerobes
needs O2 to work
What are the 4 aerobic bacteria
Nocardia
Pesuomonas
Mycobacterium tuberculosis
Bodetella pertussis
What are the 10 catalase positive bacteria
Nocardia Pseudomonas Listeria Aspergillus Candida E. coli Staph Serratia B. cepacia H. pylori
How does protein A work
Binds Fc region of IgG
Prevents opsonization/phagocytosis
S. aureus
What virulence factor binds Fc region of IgG to prevent opsonization/phagocytosis
Protein A
S. aureus
How does IgA protease work
Cleaves IgA
allows bacteria to adhere to and colonize mucous membranes
pneumococcus
H. flu
Neisseria
What virulence factor cleaves IgA and allows adherence and colonization of mucous membranes
IgA protease
pneumococcus
H. flu
Neisseria
How does M protein work
Helps prevent phagocytosis
- GAS
- shares similar epitopes to human cellular proteins (molecular mimicry)
- possibly underlies autoimmune response seen in acute rheumatic fever
What virulence factor helps prevent phagocytosis via molecular mimicry
Protein M
GAS
Biolfilm on catheter and prosthetic device infections
S.epidermidis