citric acid cycle/ox. phosphorylation Flashcards

1
Q

Each glucose generates

A

2 acetyl-coA
4 CO2
24 ATP

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2
Q

pyruvate comes from

A

glucose

amino acids

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3
Q

What does alpha ketoglutarate DH do

A

converts alpha ketoglutarate to succinylcholine-coA

redox rxn that makes NADH and CO2

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4
Q

What does alpha ketoglutarate need to work

A
Thiamine
lipolic acid
coenzyme A
FADH2 
NADH
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5
Q

how many ATPs are made from the citric cycle

A

12

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6
Q

What does isocitrate DH do

A

converts isocitrate to alpha-ketoglutarate

redox rxn that makes NADH and CO2

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7
Q

isocitrate DH is inhibited by

A

ATP
NADH
if inhibited, citrate will build up and go out into cytosol and inhibit PFK-1 from glycolysis except in liver where insulin activates PFK-2 and overrides inhibited PFK-1 to go forth with glycolysis

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8
Q

Citrate is involved in the

A

TCA cycle

FA synthesis

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