Fructose Flashcards
1
Q
Sucrose is broken down into
A
glucose
fructose
2
Q
Where does fructose go to in the body
A
liver
kidney
3
Q
What is the first enzyme in fructose metabolism
A
Fructokinase
makes fructose 1-P
traps fructose in the cell
needs ATP
4
Q
What is fructokinase deficiency
A
benign essential fructouria (AKA)
5
Q
What is the second enzyme in fructose metabolism
A
Aldolase B
turns fructose 1-P to DHAP and glyceraldehyde
presents as baby that was breast fed and fine for 6 months then suddenly becomes jaundiced and vomits after starting formula feeding
6
Q
What can DHAP go into
A
glycolysis
glycogenesis
gluconeogenesis
7
Q
What does glyceraldehyde have to become before going into glycolysis, glycogenesis, and gluconeogenesis
A
glyceraldehyde-3-P
8
Q
How does aldolase B deficiency present
A
(hereditary fructose intolerance) lethargy vomiting liver damage hypoglycemia hyperuricemia renal proximal tubule defect (Fanconi)
9
Q
Breast milk has
A
lactose no fructose
