exotoxins

Question 1

Which bacteria inactivate EF-2 as their exotoxin, inhibits protein synthesis

Answer 1

C.diptheriae - diphtheria toxin

P. aeruginosa - exotoxin A

Question 2

Which bacteria inactivate the 60S ribosome by removing adenine from rRNA, inhibits protein synthesis

Answer 2

Shigella - shiga toxin

EHEC - shiga-like toxin

Question 3

ETEC exotoxin that over activates adenylate synthase, increase cAMP, increase Cl secretion I’m the gut, and H2O efflux

Answer 3

Heat labile
watery diarrhea

“labile in the air”

Question 4

ETEC exotoxin that over activates guanylate cyclase, increases cGMP, decreases resorption of NaCl and H2O in the gut

Answer 4

Heat stable
watery diarrhea

“stable on the ground”

Question 5

Which bacteria mimics adenylate cyclase, increases cAMP

Answer 5

Bacillus anthraces - edema factor

edematous borders of black eschar in cutaneous anthrax

Question 6

Which bacteria over activates adenylate cyclase, increasing cAMP by permanently activating Gs

increases Cl secretion in gut and H2O efflux

Answer 6

Vibrio cholerae - cholera toxin

voluminous rice water diarrhea