Metabolism Part 1 Flashcards

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1
Q

the sum total of all chemical reactions occurring in the cell

A

metabolism

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2
Q

breakdown of larger complex molecules into smaller ones, energy is released

A

catabolism

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3
Q

the synthesis of complex molecules from simpler ones using energy

A

anabolism

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4
Q

occur as a series of chemical reactions using intermediates to convert the starting molecules to products

A

metabolic pathways

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5
Q

these make reactions of life possible at livable temperatures
also mediate the steps in metabolic pathways

A

enzymes

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6
Q

what are the enzymes doing

A

acting as catalysts

catalyze reaction by lowering activation energy

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7
Q

energy required to form transition state complex

A

activation energy

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8
Q

are enzymes consumed in reactions

A

no

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9
Q

this is the region where the substrate(s) attach

A

active site

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10
Q

enzyme conformation changes as substrates enter, closing around substrates

A

induced fit

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11
Q

how are enzymes classified

A

based on the type of chemical reaction catalyzed

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12
Q

Non protein component needed for functioning enzyme

Ex/ magnesium, zinc, copper

A

Cofactors

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13
Q

Organic cofactors
Act as carriers for molecules or electrons
Not as specific as enzymes
May act with numerous enzymes

A

Coenzymes

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14
Q

What are the three regulation

A

Non competitive inhibition
Competitive inhibition
Feedback inhibition

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15
Q

Inhibitor and substrate act on different enzyme sites

Allosteric vs feedback inhibition

A

Non competitive inhibition

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16
Q

Inhibitor competes for active site with the substrate

Inhibitor is structurally similar to the substrate

A

Competitive inhibition

17
Q

Product of a series of enzyme controlled reactions

Inhibits the first enzyme in the pathway

A

Feedback inhibition

18
Q

What is the capacity to do work

A

Energy

19
Q

Exists as potential and kinetic energy

Microbes use various energy sources (light, organic and inorganic molecules)

A

Harvesting energy

20
Q

This releases energy

Example is burning sugar

A

Exergonic reactions

21
Q

Use energy to produce the products

A

Endergonic reactions

22
Q

What is the currency of the cell

A

ATP

23
Q

Where is energy held

A

I’m high energy bonds between phosphate groups

24
Q

Production of ATP

A

1) substrate level phosphorylation
2) oxidative phosphorylation
3) photophos phorylation

25
Q

This uses chemical energy to add phosphate ion to molecules of ADP

A

Substrate level phosphorylation

26
Q

Uses energy from proton motive force to add phosphate ion to ADP

A

Oxidative phosphorylation

27
Q

Utilized radiant energy from sun to convert phosphorylation ADP to ATP

A

Photophosphorylation

28
Q

These are reactions in which there is a transfer of one or more electrons between reactant molecules

A

Oxidation reduction reactions

29
Q

A molecule on which electrons are parked

Transport energy from one point in the cell to another

A

Electron carriers

30
Q

What are the three important electron carriers

A

NAD+
FAD
NADP+

31
Q

What are the three key pathways

A

Glycolysis, pentose phosphate pathway, tricarboxcylic acid cycle

32
Q

What are the central pathways

A

Catabolic

33
Q

Pathways modify organic molecules to form what

A

High energy intermediates to synthesize ATP
intermediates to generate reducing power
Intermediates and end products as precursor metabolites

34
Q

What is glycolysis also called

A

Embden myerhoff pathway

35
Q

In general what does glycolysis do

A

Oxidizes glucose to two molecules of pyruvate

36
Q

What are the two phases of glycolysis

A

Preparation and energy harvest

37
Q

During this add two phosphates from ATP to 6 carbon sugar

I’m bacteria, first ATP added during group transports through membrane

A

Preparation

38
Q

Two 3C molecules rearranged to pyruvate

Each produces 2 ATP and 1 NADH

A

Energy harvest