Metabolism Flashcards

1
Q

Metabolism

A

all the chemical reactions in an organism

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2
Q

Anabolic

A

Build up

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3
Q

Catabolic

A

Break down

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4
Q

Energy

A

capacity to cause change

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5
Q

Kinetic energy

A

energy associated with motion

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6
Q

Thermal energy

A

kinetic energy associated with random movements of atoms or molecules

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7
Q

Heat

A

thermal energy in transfer from one object to another

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8
Q

Potential energy

A

energy that matter possesses because of its location or structure

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9
Q

Chemical energy

A

potential energy available in chemical reactions

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10
Q

1st law of thermodynamics

A

energy cannot be created or destroyed (conservation of energy)

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11
Q

2nd law of thermodynamics

A

As energy gets transferred around, things go form ordered to disordered, nothing is 100% efficient (disorder always increases)

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12
Q

Entropy

A

disorder, randomness

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13
Q

organism create…
in this process…

A

organism create ordered products but the universe continuous to become more disordered. In the process of making ordered products, disordered by-products are released.

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14
Q

gibbs free energy

A

energy to do work, energy in a system available to work
change in G = G final - G initial

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15
Q

change in G is positive…

A

final change in energy state has more energy, energy put in during the process

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16
Q

change in G is negative

A

energy is lost to the environment could do work elsewhere, disorder higher in final state

17
Q

spontaneous

A

energetically favorable, not necessarily fast. can occur (slowly) as long as change in G is negative

18
Q

maximum stability =

A

equilibrium (a system at equilibrium does no work) a process can only proceed spontaneously if it is moving towards equilibrium

19
Q

Exergonic reaction

A

energy released (exit), spontaneously (change in G is NEGATIVE)

20
Q

Endergonic reaction

A

energy required, non spontaneous (change in G is POSITIVE)

21
Q

3 kinds of work

A

chemical: build up molecules
transport: active transport
mechanical: microtubule movement or muscle contraction

22
Q

Energy coupling

A

using an exergonic process to drive an endergonic one

23
Q

Phosphorylation

A

transferring a phosphate group

24
Q

Enzymes

A
  • speed up chemical reactions by lowering the activation energy
  • do not participate in the reaction itself
  • are not modified by the reaction
25
Q

activation energy

A

energy required to get the reaction to proceed, enzymes LOWER the activation energy, allowing the reaction to proceed faster

26
Q

Active Site can lower activation energy by…

A
  • orienting substrates correctly
  • straining substrate bonds
  • providing a favorable microenvironment
  • covalently bonding to the substrate
27
Q

Effects on enzymes

A
  • temperature
  • pH
  • cofactors (inorganic)
  • coenzymes (organic)
28
Q

Competitive Inhibition

A

active site filled by a mimic normal substance cant gain access –> compete with normal substance

29
Q

Noncompetitive Inhibition

A

bind to a different part of the enzyme, cause enough of a change that active site isn’t accessible to normal substrate

30
Q

Allosteric regulation

A

protein function/stability by binding of a regulatory molecule on a separate site. “inhibitor” molecule binds on inactive from, stabilizes it

31
Q

Allosteric Activation

A

“activator” or regulatory molecule binds on active from and stabilizes it, now open for business basically

32
Q

Cooperativity

A

when actual substrate binding influences further binding in other active sites

33
Q

Feedback inhibition

A

product turns off process, tells system you have made enough, you can stop now