Metabolic System Flashcards
1
Q
Metabolic System
A
-physical and chemical process transforming food into energy and elements for cellular rebuilding
2
Q
Phases of Metabolism
A
- anabolic
- catabolic
3
Q
Metabolic system helps with maintaining
A
- fluid and electrolyte balance
- (and homeostasis)
- -osmotic pressure
- -acid-base balance
- -Anion-cation balance
4
Q
Metabolic Disorders
A
- any problem in body that causes loss of metabolic control of the body’s steady state
- most are inherited (autosomal recessive)
5
Q
Ex. Metabolic Disorders
A
- Paget’s Disease
- Phenylketonuria (PKU)
- Metabolic Syndrome
- Obesity
6
Q
Paget’s Disease
A
- bone cells increase in number, become larger and more active
- Osteoblast defect
- Bone turnover incr up to 40x and new bone is abnormal in shape/structure/weaker
7
Q
Paget’s Disease S/Sx
A
- headache
- deep boring constant pain
- CN VIII can be involved
- hearing loss
8
Q
Paget’s Disease Tx
A
- PT (incr mm strength, pn control, low/no impact WB)
- pharmacological (bisphosphonates)
- Pain management (analgesics)
- surgery
9
Q
PKU
A
- Phenylketonuria
- genetic disease
- phenylalanine builds up in circulation–>brain damage
10
Q
genetic component of PKU
A
- caused by mutations in the gene coding for phenylalanine hydroxylase enzyme
- phenylalanine builds up in blood
11
Q
Newborn infants routinely screened for ______
A
- PKU
- tested by blood tests
12
Q
PKU S/Sx
A
-mousy odor
13
Q
Metabolic Syndrome Diagnosis
A
3 of 5 of below:
- central obesity
- HTN
- High Triglycerides
- low HDL
- Insulin resistance
14
Q
Metabolic Syndrome Management
A
- decr sodium intake
- diet
- exercise
- control HTN
- weight loss
15
Q
Waist-to-Hip Ratio
A
-waist circumference index to determine risk for metabolic syndrome
Male: >102 cm (ratio >0.8 = central obesity)
-Female: >88 cm (ratio >1.0 = central obesity)
