Menstrual Disorders Flashcards

1
Q

what hormone stimulates ovarian follicle development and oetrogen production

A

FSH

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2
Q

which cells produce oestrogens

A

grandulosa cells

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3
Q

what happens as a results of raising oestrogen and inhibin by dominant follicles

A

inhibits FSH

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4
Q

what do declining FSH levels cause

A

atresia of dominant follicle

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5
Q

when does ovulation occur

A

prior to LH surge - dominant follicle rupture and releases oocyte

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6
Q

what occurs in the luteal phase

A

formation of the corpus luteum
progesterone production
luteolysis 14 days post ovulation

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7
Q

what are the phases that the endometrium goes through during the cycle

A

proliferative
luteal
menstruation

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8
Q

which hormone mediates the proliferative phase

A

oestrogen

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9
Q

which hormone mediates the luteal phase

A

progesterone

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10
Q

what are the mechanisms of menstruation

A

arteriorlar constriction results in shedding of the endometrial layer
fibrinolysis inhibits scare tissue formation

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11
Q

how long does menstrual loss usually last

A

4-6 days

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12
Q

what is the usual blood loss in menstruation

A

less than 80ml

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13
Q

what is the length of an average cycle

A
28 days
(21-35days =normal)
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14
Q

define the term menorrhagia

A

prolonged and increased menstrual flow

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15
Q

metrorrhagia

A

regular intermentrual bleeding

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16
Q

polymenorrhoea

A

menses occurring at less than 21 day intervals

17
Q

polymenorrhagia

A

increased bleeding and more frequent cycle

18
Q

menometrohagia

A

prolonged menses and intermentrual bleeding

19
Q

amenorrhoea

A

absence of menstruation for more than 6 months

20
Q

oligomenorrhea

A

menses at intervals of more than 35 days

21
Q

what is the term for menorrhagia with no organic cause and how common is it

A

dysfunctional uterine bleeding

50 percent of cases

22
Q

what local causes can cause menorrhagia

A
fibroids
adenomyosis
polyps
cervical eversion
endometrial hyperplasia
IUD
pelvic inflammatory disease
endometriosis
malignancy
hormone producing tumours
trauma
arteriorvenous malformations
23
Q

what is endometriosis

A

a conditions where parts of the womb lining are found outside of the womb

24
Q

what is an ovarian endometrioma

A

benign oestrogen dependent cyst found in woman of reproductive age

25
Q

what systemic disorders can cause menorrhagia

A
thyroid disease
diabetes
adrenal disease
prolactin disorders
von willebrand's
ITP
clotting factor deficit
anticoagulant drugs
pregnancy - miscarriage, ectopic, gestational trophoblastic disease, PPH
26
Q

what are the two types of dysfunctional uterine bleeding

A

anovulatory (irregular cycle) - 85 percent

ovulatory (regular cycle)