Menopause Flashcards

1
Q

What is menopause ?

A

The end of female reproductive life

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2
Q

Average age

A

51

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3
Q

Early menopause - age

A

Below 45

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4
Q

Late menopause - age

A

Above 54

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5
Q

Pathogenesis

A

Reduction in circulating oestrogen levels

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6
Q

FSH and LH levels increase/decrease during menopause? Why is this?

A

Increase

  • FSH and LH are telling ovaries to release an egg but ovaries aren’t listening.
  • stronger surge of FSH and LH to try and get an egg to release
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7
Q

Vasomotor symptoms

A

Hot flushes - last for 3-5 mins each
Night sweats
Palpitations
Insomnia

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8
Q

Physical symptoms

A

Headaches
Anxiety
Difficulty concentrating
Forgetfullness

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9
Q

Sexual symptoms

A

Vaginal dryness

lack of Libido

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10
Q

Urogenital symptoms

A

Frequency
Recurrent UTIs
Urinary incontinence

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11
Q

How do you make a diagnosis in a patient over 45

A

Clinical diagnosis

  • based on symptoms
  • pattern of periods
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12
Q

How do you make a diagnosis in a patient with suspected menopause who is under 45 ?

A

Clinical findings + blood tests required

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13
Q

Perimenopausal dysfunctional uterine bleeding examples

A

Irregular periods
Intra-menstrual bleeding
Post-menopausal bleeding

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14
Q

Post-menopausal bleeding is treated as _____ until proven otherwise?

A

Endometrial cancer

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15
Q

Management of menorrhagia

A

Mefenamic acid
Tranexamic acid
Progesterones
Hysterectomy

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16
Q

Management of menorrhagia - menorrhagia - mefenamic acid

A

NSAID
Reduces the blood supply to the womb
Only take on period days

17
Q

Management of menorrhagia - tranexamic acid

A

Anti-fibrinolytic

Bleed less

18
Q

Management of vasomotor symptoms

A

HRT

  • oestrogen alone
  • oestrogen + progesterone
19
Q

List 3 risks of HRT

A

VTE
CVA
Breast cancer

20
Q

Alternative mangement to HRT for vasomotor sympotms

A

Clonidine

SSRI