Membrane Structure and Function Flashcards
Cholesterol
Stiffens and strengthens the membrane, therefore helping to regulate its fluidity
Plasma membrane structure
Membrane is composed of phospholipid bilayer (where proteins are embedded)
Hydrophobic tails face inwards to make up the interior of the membrane, hydrophilic heads face outwards
Carbohydrate chains are attached to the outside surface
Cytoskeleton filaments are attached to the side surface
Integral Proteins
Have specific functions inside of the membrane
Channel Protein
Allows particular molecules to cross the membrane freely
Cystic fibrosis is cause by a faulty chloride channel
Carrier Protein
Selectively interacts with specific molecule or ion to freely pass
Inability to transport (NA+-K+) can be the cause of their obesity
Selective
Cell Recognition Protein
The MHC glycoproteins are different for each person, which is why finding matching transplants are difficult
Cells with foreign MHC are attacked by white blood cells
Receptor Proteins
Shaped in such a way that specific molecules can bind to it
Some types of dwarfism are the result of faulty hormone receptors
Enzymatic Proteins
Catalyzes a specific reaction
Cholrea because releases a toxin that interferes with adenylate cyclase, which leads to severe diarrhea
Differentially permeable
Certain substances can move across the membrane while others can’t
Concentration gradient
Molecules move from an area of high concentration to an area of low concentration
Permeability of the plasma membrane
Differentially permeable
Molecules that can’t be transported freely are moved through channel proteins or vesicle formation
Vesicle formation
Another way molecules can enter (endocytosis) or exit a cell (exocytosis)
Diffusion
Movement of molecules from a higher concentration to an area of low concentration
Factors influcening the rate of diffusion
Temperature
Pressure
Electrical currents
Molecular size
Osmosis
Diffusion of water across a differentially permeable membrane
Isotonic solutions
Solute concentration and water concentration both inside and outside the cell are equal and therefore there is no net gain or loss of water
Hypotonic solution
Solutions that cause cells to swell or even burst, due to intake of water