Medicinal Chemistry Flashcards
1
Q
Macrolide structure components
A
Three main parts
Macrocyclic lactone + Ketone group + 2 aminodeoxysugars
2
Q
Benzothiadiazine structure
A
Hydrochlorothiazide
3
Q
Gamma aminobutyric acid + cyclohexane ring
A
Gabapentin
4
Q
What is DPP4 inhibitors structure?
A
Quinazolidone structure and Cyanopyrrolidine structure
5
Q
What is the structure feature of adrenocorticoids
A
From C-21 pregnant Steroidal Nucleus
17 B ketoacidosis side chain COCH2OH
3 ketone
4 ene
6
Q
What are the features of 5alpha reductase inhibitors?
A
Dutasteride= NH group in first ring, NH group substitute ,ring with 2CF3
Finasteride= NH group in first ring, NH substitute.
