Drugs Side Effects Flashcards

1
Q

Leflunomide SEs

A

Sever liver injury
Interstitial lung disease
Myelosupression

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2
Q

Isotretinoin side effect

A

Teratogenic ( baseline preg. test every month and 2birth control methods)
Increase cholesterol and triglycerides , (Monitor)
Liver ( LFT)
Depression

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3
Q

Conditions cause Dry mouth

A

Sjorgen syndrome
Biliary cholangitis
Uncontrolled diabetes
Crohn’s disease

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4
Q

Condition cause excess salivation

A

Parkinson’s

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5
Q

Condition cause alopecia

A

Syphilis

Treatment by penicillin, doxycycline, ceftriaxone

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6
Q

Diltiazem side effects

Nb..it is coronary artery VD

A

Dizziness
Brady cardia
Heart block
Heart failure - Negative inotropic effect

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7
Q

Phenothiazines antipsychotics

A

Tardative dyskinesia

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8
Q

Drugs causing pulmonary fibrosis

A
Amiodarone
Bromocriptine
Bleomycin
Busulfan
Leflunamide
Nitrofurantoin
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9
Q

Side effects of corticosteroids

A

Hyperglycemia
Hypertension
Hypokalemia
Osteoporosis

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10
Q

Gemfibrazil side effect

A

Cholelithiasis and gallstone formation

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11
Q

Priapism is a side effect from

A

PDE 5 inhibitors
Trazodone
Alprostadil
Fluoxetine

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12
Q

Side effect of lithium

A
TREMOR, 
Polydypsia
Diarrhea affect thyroid gland
Nausea and Vomiting 
Weight loss/gain ??
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13
Q

Drugs cause Photosensitivity

A
Chlorpromazine 
1st generation antipsychotics
Hydrochlrothiazide THIAZIDES
Retinoids
Tetracycline 
PUVA-Psoralens (Methosalen, Oxsoralen). 
Coal Tar
Valproic acid
Amiodarone 
Sulfamethoxazole+ Trimethoprim
St. John warts
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14
Q

Side effects of Leflunamide

A

For RA ( inhibit DHODH)

Weight loss
Rash
Alopecia
Hypokalemia
Hepato Toxic
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15
Q

Drugs associated with Intracranial Hypertension

A
Sulfamethoxazole- Trimethoprim
Tetracycline 
Minocycline
Isotretinoin 
Cimetidine
Tamoxifen
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16
Q

Warfarin + Gemfibrozil

A

Increase INR and bleeding

17
Q

Gemfibrate & Simvastatin

A

Myopathy

Rhabdomyolysis

18
Q

Antipsychotic with least EPS esp parkinsonian

A

Clozapine

Quetiapine

19
Q

What are the side effects of anastrazole and letrozole?

A

Hot flashes
Osteoporosis
Cardiovascular events
Not used in premenopausal or pregnant women 🤰🏻

20
Q

What are the side effects of Tamoxifen?

A
SERM used for Breast Cancer
It inhibit CYP3A4 and P glycoprotein.
Hot flashes, vaginal bleeding, 
Hypercalcemia- Stop therapy
Thromboembolism
Vision is affected
21
Q

What are the drugs that affect thyroid functions.

A

Warfarin
Heparin
Amiodarone
Lithium

22
Q

What is the side effect of cyclosporine (Kidney transplant)

A
Renal dysfunction
Hypertension
Hyperlipidemia
Tremor and headache
HyperTrihosis 👹
Gum hyperplasia
23
Q

What are the side effects of leflunamide

A
Diarrhea , Nausea
Weight loss
Flu🤧like symptoms
Skin rash
alopecia👴🏻
Hypo Kalemia
24
Q

What are the uses of penicillamine?

A
Urticaria and rash
Diarrhea💩
Bone marrow depression (thrombocytopenia and leucopenia)
Tinnitus
Protein urea