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Mona Practice :) > Mech Of Action > Flashcards

Mech Of Action Flashcards

1
Q

DPP 4 inhibitors

A

Saxigliptine, Sitagliptin, Linagliptine

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2
Q

Prucalopride

A

5 HT4 receptor agonist = prokinetic

Treatment of idiopathic chronic constipation in females

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3
Q

Nystatin mechanism

A

Bind to ergosterol cause pores

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4
Q

Inhibit glucan synthetase that forms B glucans.

A

Echinochandins
Caspofungin
Anidulafungin
Micafungin

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5
Q

5 flucytosine

A

Is converted to 5 florouracil - Pyrimidine analog- inhibit DNA synthesis

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6
Q

Calcinuerin inhibitors ( protein phosphate that activate T cell)

A

Cyclosporine

Tacrolimus

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7
Q

Alpha 1A receptor antagonist

A

Alfuzosin

Silodosin

Tamsulosin

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8
Q

5HT 1b/1d receptor Agonist

A

Sumatriptan
Rizatriptan
Zolmitriptan
Naratriptan

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9
Q

Direct Thrombin (IIa) Inhibitor

A

Dabigatran. Oral

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10
Q

GLP1 analogues

A

Liraglutide- once daily inj

Exenatide-twice daily

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11
Q

SGLT2 inhibitors

A

Canagliflozin

Dapagliflozin

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12
Q

Cholestrylamine mechanism of action

A

Anion exchange resin bind with enzyme in intestine and inhibit cholesterol synthesis.

Decrease LDL, increase HDL
Increase TG. العبيط

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13
Q

What is secreted by the adrenal gland.

A

Adrenal Cortex
Glomerulosa-Aldosterone
Fasciculata-Cortisol
Reticularis - Androgens

Adrenal Medulla - Epinephrine/ Norepinephrine

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14
Q

Progesterone Antagonist

A

Mifepristone

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15
Q

Weak androgen for treatment of endometriosis

A

Danazol

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16
Q

Synthetic progestin with potent antiandrogenic property

A

Cyproterone acetate

Used for hairsutism
Acne
Virulizing Syndrome
Precocious puberty in boys

17
Q

Leflunamide

A

Inhibit Dihydro Orate Dehydrogenase needed for Pyrimidine synthesis

For treatment of Rheumatoid Arthritis

18
Q

Triggers for release of ADH?

A

Hyperosmolarity

High Na level

Dehydration

19
Q

Function of ADH

A

Decrease Urine
Decrease sweating
Increase Blood Pressure

20
Q

What is Pinaverium Bromide?

A

GIT calcium antagonist , antispasmodic in IBS

21
Q

What is the mechanism of action of Trazodone and Nafazadone

A

Seratonin reputable inhibitors
Block 5HT2a
Block H1-Sedation
Block a1 -orthostasis

Trazodone -priapism
Nafazadone- hepatotoxic

Mona Practice :) (24 decks)

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