Mastitis/Avian Flashcards
What is the BTSCC of a healthy gland?
<100,000 cells/mL
mononuclear cells mostly present
What is the BTSCC of an infected gland?
200,000+ cells/mL mainly PMN (neutrophils)
What are the results that commonly come back from a subclinical mastitis test?
CMT neg
CMT trace
CMT 1
What is the predominant form of contagious mastitis?
Subclinical mastitis
What is the legal limit of BTSCC for grade A milk?
750,000 cells/mL
T/F: Mild clinical mastitis is not obvious unless the milk is stripped
True
Predominant form-mild clinical mastitis
What type of clinical mastitis is seen when there is change in the milk and inflamed gland?
Moderate clinical mastitis
What is the least common form of clinical mastitis that is characterized by changes in milk, inflamed gland and sick cow?
Severe clinical mastitis
What is the difference in number of mammary glands in cows vs. small ruminants?
Cows: 4 glands
SR: 2 glands
What are some methods the body will try and combat mastitis infections?
Antibacterial enzymes Lactoferrin Cytotoxic lymphocytes Low O2 tension Complement IgG
What is the reservoir for contagious mastitis?
Mammary gland- acquired from milk-contaminated fomites & spread from cow to cow at milking time
How can bacteria be introduced to the mammary gland during milking?
Teat liner slips –> reverse pressure gradient produced –> organisms can then enter the gland
What is the most accurate method of teat sanitization in contagious mastitis?
Post-dipping (germicidal solution)
What is the most important aspect of prevention for contagious mastitis?
Biosecurity and Management
What are the 3 major pathogens in contagious mastitis?
Streptococcus agalactiae
Staphylococcus aureus
Mycoplasma bovis
What is the minor pathogen in contagious mastitis?
Corynebacterium bovis
What are the blood agar results with Strep, Staph and Corynebacterium?
Strep: cAMP positive
Staph: coagulase positive
Corynebacterium: rods
Which pathogen involved with contagious mastitis requires special media?
Mycoplasma bovis
What is the tx for contagious mastitis?
Intra-mammary Ab during lactation or start of dry period
Which pathogens of contagious mastitis are easiest –> most difficult to tx?
Corynebacterium > Strep > Staph > Mycoplasma
Herds that have Mycoplasma strain of mastitis may also have what three other problems associated with the bacterial infection?
Polyarhtritis
Respiratory disease
Otitis media
What is the reservoir for environmental mastitis?
Environment
When is environmental mastitis acquired?
Between milking or during dry period
When is the highest risk for contracting environmental mastitis?
At dry-off and right before parturition
WHat are the common major pathogens of environmental mastitis?
Coliform bacteria (E. coli & Klebsiella), Streptococci
What is the uncommon major pathogen of environmental mastitis?
Environmental bacteria
Fungi/yeast
Algae
How should environmental mastitis be controlled?
Reduce pathogen load in the environment through good management practices
Frequent pasture rotation
Avoid overcrowding
Good ventilation
What type of bedding supports bacterial growth?
Organic materials (sawdust, straw, recycled material)
What are some preventative actions that can be taken on the cow for environmental mastitis?
Pre-dipping (prevents liners from being contaminated)
Teat sealant during dry period
What type of mastitis is there a vaccine available for?
Environmental mastitis (core antigen vaccine) Stimulate immunity against Gram Neg LPS antigens
T/F: Core antigen vaccine for mastitis prevents mastitis formation from ever occurring?
FALSE
Will still get infection but it is less severe for coliform mastitis
NO VACCINE FOR ENVIRONMENTAL STREP MASTITIS
What fraction of milk cultures from mastitis has no growth?
1/3
What is the recommended tx for environmental mastitis?
Support therapy and frequent stripping
What is the typical presenting complaint of contagious mastitis?
High/increasing bulk tank SCC