Management of Diabetes D - Type 2 Diabetes Mellitus - Part 1 Flashcards
what health care specialists may be involved in managing a patient with diabetes
practice nurse GP diabetes consultant podiatrist ophthalmoligist
what are symptoms of uncontrolled type 2 diabetes
frequent urination thirst hunger drowsy tingling/numbness hands/feet blurry vision
what is the first choice treatment in type 2 diabetics
metformin
what is the action of metformin
decreases blood glucose
enhances response to insulin
what is the second choice treatment in type 2 diabetes
Sulfonylureas
how does sulfonylurea work
lower blood glucose by stimulating insulin release form Beta cells
what are advantages of using metformin
improves cardiovascular outcomes
cheap
effective
well tolerated
what is a disadvantage of using metformin
risk of lactic acidosis by inhibiting lactic acid uptake by the liver
GI side effects
what are advantages of sulphonylurea
can be used with metaformin
rapid improvement in control
rapid improvement in symptoms
cheap
what are disadvantages of using sulphonylurea
risk of hypoglycaemia
weight gain
what are thiazolidinediones
oral antidiabetic drugs
treat type 2
target insulin resistance
what are advantages of using thiazolidinediones
good for patients if insulin resistance is significant
cheap
CV safe
what are disadvantages of using thiazolidinediones
increased risk of bladder cancer
weight gain
fluid rentention
