Malassezia Flashcards
Which Malassezia species has both a yeast and mycelial phase?
Malassezia furfur
Is Malassezia patchydermatis lipophilic or non-lipophilic?
Lipophilic
In what breeds might you find Malassezia patchydermatis most commonly?
- Basset hound
- Dachshund
- Boxer
- American cocker spaniel
Malassezia dermatitis is typically a secondary problem. What 4 diseases are typically associated with this fungal infection?
- Allergies
- Endocrinopathies
- Cornification disorders
- Systemic illnesses
True or False: Malassezia is pruritic.
TRUE - progressively pruritic
What are the historical complaints associated with a Malassezia infection?
- Licking feet
- Rubbing face
- Weight loss
- Perianal pruritus
- Otitis externa
Is Malassezia responsive to glucocorticoids?
Partially responsive, but that responsiveness wanes
What are the 4 differental diagnoses of intense pruritus in the dog?
- Scabies
- Malassezia dermatitis
- Flea allergy dermatitis
- Seborrhea
Of the 4 differential diagnoses of intense pruritus, which is most commonly seen?
Malassezia dermatitis
What are the key physical features associated with a Malassezia infection?
- Pruritus
- Erythema
- Scaling
- Crusting
- Lichenification
- Hyperpigmentation
- Alopecia
- Lymph node enlargement
For Malassezia, which treatment is best, topical or systemic?
Topical
___ ___ is used to reduce greasiness associated with Malassezia.
Selenium disulfide
How frequent should shampoo therapy be done to control Malassezia?
3 X weekly as a sole therapy
1-2 X weekly as adjunct therapy
What is the most important key to shampoo therapy with Malassezia?
Contact time
What are the ingredients in Mal-a-Ket?
- Ketoconazole
- Chlorhexidine
- Acetic acid
What are the ingredients in Malacetic ultra?
- Hydrocortisone
- Ketoconazole
- Acetic acid
- Boric acid
What are the ingredients in Malaseb?
- Miconazole
2. Chlorhexidine
What are the 4 systemic antifungals?
- Ketoconazole
- Itraconazole
- Fluconazole
- Terbinafine
What is the duration of treatment for a systemic antifungal?
21-30 days
What is the mechanism of action of ketoconazole?
P-glycoprotein inhibitor and P450
What are the 3 side effects associated with Terbinafine?
- GI
- Panting
- Increased hepatic enzymes
True or False: Malassezia therapy should be discontinued after 30 days.
FALSE - therapy should never be completely discontinued.