Malaria - Therapy and Side Effects Flashcards
Lumefantrine
Therapy?
Therapy: used in combination with Artemether for treatment of severe malaria
Hydroxychlorquine
Therapy?
prophylaxis, treatment of acute malarial attacks
Atovaquone
Therapy?
used in combination with Chloroguanide (Proguanil)
Chloroquine
Therapy? Side Effects?
Therapy: prophylaxis, treatment of acute malarial attacks
Side Effects: itching (Africans); retinitis (rare)
Tetracycline
Therapy?
Therapy: severe malaria and chloroquine-resistant uncomplicated malaria
Quinine
Therapy? Side Effects?
Therapy: prophylaxis, treatment of acute malarial attacks
Side Effects: cinchoism; hypotension; abortion; arrythmias
Clindamycin
Therapy?
Therapy: severe malaria and chloroquine-resistant uncomplicated malaria
Artesunate
Therapy? Side Effects?
Therapy: severe malaria
Side Effects: neurotoxicity; QT prolongation
Mefloquine
Therapy?
Therapy: prophylaxis, treatment of acute malarial attacks
Artemether
Therapy?
Therapy: severe malaria
used in combination with Lumefantrine
Primaquine
Therapy? Side Effects?
Therapy: prophylaxis, treatment of acute malarial attacks
Side Effects: hemolysis (in patients w G6PD deficiency); methemoglobinemia
Doxycycline
Therapy? Side Effects?
Therapy: severe malaria and chloroquine-resistant uncomplicated malaria
Side Effects: photosensitivity
Chloroguanide (Proguanil)
Therapy?
Therapy: combination therapy with Atovaquone for malaria
Pyrimethamine
Therapy?
Therapy: combination therapy
Hydroxychloroquine
Therapy?
Therapy: prophylaxis, treatment of acute malarial attacks