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Pharmacology, Unit 2 > Adrenergic MOA > Flashcards

Adrenergic MOA Flashcards

1
Q

Receptors we’re about to deal with

A
  1. a1- vasoconstriction
  2. a2- Decreased sympathetic tone
  3. b1- Increase HR, force of contraction
  4. b2- Vasodilation, bronchodilation
  5. D1- Renal, Mesenteric, Cerebral arteriolodilation
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2
Q

Epinephrine

A

Nonselective Agonist: a1, a2, b1, b2

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3
Q

Norepinephrine

A

Nonselective Agonist: a1, a2, b1

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4
Q

Amphetamine

A

Indirect acting agonist; Increases release of NE

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5
Q

Isoproterenol

A

Nonselective Beta Agonist: b1, b2

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6
Q

Dobutamine

A

b1 Selective Agonist

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7
Q

Albuterol

A

b2 Selective Agonist

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8
Q

Terbutaline

A

b2 Selective Agonist

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9
Q

Phenylephrine

A

a1 Selective Agonist

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10
Q

Clonidine

A

a2 Selective Agonist

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11
Q

a-methyldopa

A

a2 Selective Agonist

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12
Q

Fenoldopam

A

D1 Selective Agonist

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13
Q

Dopamine

A

Mixed Acting Agonist: D1, a1, b1

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14
Q

Phentolamine

A

Nonselective Alpha Antagonist: a1, a2

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15
Q

Phenoxybenzamine

A

Nonselective Alpha Antagonist: a1, a2

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16
Q

Prazosin

A

a1 Selective Antagonist

17
Q

Terazosin

A

a1 Selective Antagonist

18
Q

Propranolol

A

Nonselective Beta Antagonist (1st gen): b1, b2

19
Q

Timolol

A

Nonselective Beta Antagonist (1st gen): b1, b2

20
Q

Metoprolol

A

b1 selective Antagonist (2nd gen)

21
Q

Atenolol

A

b1 selective Antagonist (2nd gen)

22
Q

Bisoprolol

A

b1 selective Antagonist (2nd gen)

23
Q

Carvedilol

A

Nonselective Beta Antagonist (3rd gen “A”): b1, b2

24
Q

Labetalol

A

Nonselective Beta Antagonist (3rd gen “A”): b1, b2

25
Q

Betaxolol

A

b1 Selective Antagonist (3rd gen “B”)

26
Q

Tyramine

A

Indirect Agonist: Increases cytoplasmic NE. Prevents NE re-uptake

27
Q

Guanethidine

A

Flase neurotransmitter

28
Q

Reserpine

A

Release of empty vesicles (?)

29
Q

a-me-tyrosine

A

Inhibits tyrosine hydroxylase

30
Q

Ephedrine

A

Mixed, direct b2/indirect agonist (??)

Pharmacology, Unit 2 (22 decks)

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