ACh-Related Therapy

Question 1

Bethanecol

Answer 1

1. Ileus (post-operative and neurogenic)

2. Urinary retention

Question 2

Muscarine

Answer 2

useless

Question 3

Pilocarpine

Answer 3

Glaucoma (ACh activates papillary sphincter and ciliary muscles of eye)

Question 4

Cevimeline

Answer 4

Dry mouth (eg, in Sjogren’s, post-radiation therapy)

Question 5

Nicotine

Answer 5

smoking cessation

Question 6

Neostigmine

Answer 6

1. ileus (post-op and neurogenic)
2. urinary retention
3. myasthenia gravis
4. reversal of neuromuscular blockade

Question 7

Physostigmine

Answer 7

Glaucoma

Question 8

Donepezil

Answer 8

Alzheimer’s

Question 9

Edrophonium

Answer 9

1. myasthenia gravis

2. ileus

Question 10

Echothiophate

Answer 10

Glaucoma

Question 11

Pralidoxime

Answer 11

1. nerve gas poison

2. insecticide

Question 12

Soman

Answer 12

nerve gas poison

Question 13

Atropine

Answer 13

Mydriasis, cycloplegia

Question 14

Scopolamine

Answer 14

Prevent, reduce motion sickness

Question 15

Dicyclomine

Answer 15

Reduce transient hypermotility

Question 16

Tropicamide

Answer 16

Mydriasis, cycloplegia

Question 17

Tolterodine

Answer 17

Transient cystitis, post-op bladder spasms, incontinence.

Question 18

Benztropine

Answer 18

Parkinson’s

Question 19

Ipratropium

Answer 19

Bronchodilation in asthma or COPD

Question 20

Tiotropium

Answer 20

Bronchodilation in asthma or COPD

Question 21

Hexamethonium

Answer 21

Hypertensive crisis; “bloodless” field surgery

Question 22

Succinylcholine

Answer 22

Brief procedures (intubation, resetting joints)

Question 23

Tubocurarine

Answer 23

Muscle relaxant for surgery w/o deep anesthesia

Question 24

Mivacurium

Answer 24

Muscle relaxant for surgery w/o deep anesthesia

Question 25

Botulinum Toxin A

Answer 25

Reduce frown lines and wrinkles; achalasia, strabismus, oromandibular dystonia