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Pharmacology, Unit 2 > Histamine & Serotonin - Mechanisms & Classes > Flashcards

Histamine & Serotonin - Mechanisms & Classes Flashcards

1
Q

Chloropheniramine

A

H1-receptor anatagonist

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2
Q

Loratadine

A

2nd-generation H1-receptor anatagonist

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3
Q

Cimetidine

A

H2-receptor antagonist (blocks gastric acid secretion, especially nocturnally)

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4
Q

Triptans

A

5-HT1-B,D receptor antagonist

class: non-ergot serotonin analogs

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5
Q

Promethazine

A

H1-receptor anatagonist

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6
Q

Fexofenadine

A

2nd-generation H1-receptor anatagonist

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7
Q

Bromocriptine

A

Dopamine agonist

Class: ergot alkaloid

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8
Q

Ranitidine

A

H2-receptor antagonist (blocks gastric acid secretion, especially nocturnally)

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9
Q

Tripelennamine

A

H1-receptor anatagonist

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10
Q

Azelastine

A

2nd-generation H1-receptor anatagonist (blocks gastric acid secretion, especially nocturnally)

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11
Q

Cyproheptadine

A

anti-Histaminergic; anti-Serotinergic

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12
Q

Methysergide

A
  1. partial agonist at 5-HT-1 receptors
  2. antagonist at 5-HT-2 receptors

class: Ergot alkaloid

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13
Q

Cyclizine

A

H1-receptor anatagonist

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14
Q

Cetrizine

A

2nd-generation H1-receptor anatagonist (blocks gastric acid secretion, especially nocturnally)

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15
Q

Famotidine

A

H2-receptor antagonist (blocks gastric acid secretion, especially nocturnally)

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16
Q

Ergotamine

A
  1. non-specific partial agonist at all 5-HT-1,2 receptors
  2. partial agonist at alpha-adrenergic receptors

class: Ergot Alkaloid

17
Q

Odansetron

A

5-HT-3 receptor antagonist

18
Q

Ketanserin

A
  1. selective 5-HT-2A, 2C receptor antagonist

2. alpha-1, H1 receptor antagonist

19
Q

Diphenhydramine

A

H1-receptor anatagonist

20
Q

Nizatidine

A

H2-receptor antagonist (blocks gastric acid secretion, especially nocturnally)

21
Q

What are the drugs that belong to the Ergot Alkaloids?

A
  1. Ergotamine
  2. Methysergide
  3. Ergonovine
  4. Bromocriptine
22
Q

What drugs are non-ergot serotonin analogs?

A

Triptans

Pharmacology, Unit 2 (22 decks)

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