Histamine & Serotonin - Side Effects Flashcards
1
Q
Cyproheptadine
A
sedation; anti-muscarinic effects
2
Q
Chloropheniramine
A
sedation, but less so
3
Q
Promethazine
A
sedation; anti-muscarinic effects
4
Q
Diphenhydramine
A
sedation; anti-muscarinic effects
5
Q
Loratidine
A
cardiovascular effects at high doses
fewer sedative and CNS effects because it poorly crosses BBB
6
Q
Fexofenadine
A
cardiovascular effects at high doses
fewer sedative and CNS effects because it poorly crosses BBB
7
Q
Azelastine
A
fewer sedative and CNS effects because it poorly crosses BBB
8
Q
Cetrizine
A
fewer sedative CNS effects because it poorly crosses BBB
9
Q
Cimetidine
A
most side effects of H2 receptor antagonists
- anti-androgen activity canc ause impotence and gynecomastia
- inhibition of P450 enzymes
- possible CNS dysfunction
10
Q
Ranitidine
A
- liver toxicity
2. possible CNS dysfunction
11
Q
Famotidine
A
possible CNS dysfunction
12
Q
Nizatidine
A
possible CNS dysfunction
13
Q
Methysergide
A
- GI disturbances
- inflammatory fibrosis
- hallucinations
