Inflammation - Side Effects

Question 1

Ibuprofen

Answer 1

GI irritation; hepatotoxicity

Question 2

Indomethacin

Answer 2

1. thrombocytopenia
2. aplastic anemia
3. severe frontal headaches
4. nephrotoxicity in elderly or hypovolemic patients

Question 3

Flurbiprofen

Answer 3

GI irritation; hepatotoxicity

Question 4

Acetaminophen

Answer 4

1. renal tubular necrosis (if abused with NSAIDs)

2. hepatic necrosis (overdose)

Question 5

Naproxen

Answer 5

GI irritation; hepatotoxicity

Question 6

Diflunisal

Answer 6

fewer GI side effects and less effect on platelets than acetylsalicylic acid

Question 7

Oxaprozin

Answer 7

GI irritation; hepatotoxicity

Question 8

Celecoxib

Answer 8

1. less GI toxicity than traditional NSAIDs

2. contraindicated during heart problems or pregnancy

Question 9

Sulindac

Answer 9

1. thrombocytopenia
2. aplastic anemia
3. severe frontal headaches
4. nephrotoxicity in elderly or hypovolemic patients

*less potent & less side effects than Indomethacin

Question 10

Acetylsalicylic Acid

Answer 10

1. GI irritation
2. bleeding
3. anemia
4. hepatotoxicity
5. salicylate toxicity

Question 11

Etoricoxib

Answer 11

1. less GI toxicity than traditional NSAIDs

2. contraindicated during heart problems or pregnancy